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Serotonin hydrochloride (CAS 153-98-0)

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Alternate Names:
Serotonin hydrochloride is also known as 5-Hydroxytryptamine hydrochloride.
Application:
Serotonin hydrochloride is the salt form of Serotonin, a monoamine tryptophan-based amino acid neurotransmitter.
CAS Number:
153-98-0
Purity:
≥98%
Molecular Weight:
212.68
Molecular Formula:
C10H12N2O•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Serotonin hydrochloride is an endogenous 5-HT agonist produced by serotonergic neurons in the CNS and enterochromaffin cells in the gastrointestinal tract. Serotonin hydrochloride is the salt form of Serotonin, a monoamine neurotransmitter biochemically derived from tryptophan. This neurotransmitter is located in the central nervous system and functions as an endogenous SR (serotonin receptor) agonist in a variety of biochemical processes. In the majority of the human bodies, serotonin is located in enterochromaffin ("Kulchitsky cells"). Serotonin is found in the gastrointestinal tract and platelets. Furthermore, Serotonin functions as a growth factor in some cells and facilitates wound healing in conjunction with platelets. Serotonin is thought to be a key component in the regulation of moods, cognition, and personality traits. As a result, Serotonin hydrochloride is essential in studying the variations in these traits.


Serotonin hydrochloride (CAS 153-98-0) References

  1. Effects of injection of serotonin into nucleus caudatus on food and water intake and body weight in albino rats.  |  Pal, GK., et al. 2004. Indian J Physiol Pharmacol. 48: 437-45. PMID: 15907052
  2. Intermolecular association provides specific optical and NMR signatures for serotonin at intravesicular concentrations.  |  Nag, S., et al. 2008. Biophys J. 94: 4145-53. PMID: 18234835
  3. Serotonin and dopamine transporters in relation to neuropsychological functioning, personality traits and mood in young adult healthy subjects.  |  Burke, SM., et al. 2011. Psychol Med. 41: 419-29. PMID: 20367893
  4. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels.  |  Licht, CL., et al. 2010. Neurosci Lett. 476: 58-61. PMID: 20381585
  5. Phagocytosis of biocompatible gold nanoparticles.  |  Krpetić, Z., et al. 2010. Langmuir. 26: 14799-805. PMID: 20795674
  6. [Simultaneous detection of 8 monoamine neurotransmitters in the different sections of rat brains by high performance liquid chromatography with fluorescence detection].  |  Zhao, Y., et al. 2011. Se Pu. 29: 146-51. PMID: 21598515
  7. Assay for acetyl-CoA:arylamine N-acetyltransferase by high-performance liquid chromatography applied to serotonin N-acetylation.  |  Mannens, G., et al. 1990. Biochim Biophys Acta. 1037: 1-6. PMID: 2294966
  8. The long-term effect of serotonin on the thermoregulatory behavior in juvenile cyprinidae (Cyprinus carpio and Carassius auratus).  |  Garina, DV., et al. 2013. Fish Physiol Biochem. 39: 1373-6. PMID: 23515758
  9. [INVESTIGATIONS OF SUBMICROSCOPIC ARCHITECTONICS SERTOLI AND LEYDIG CELLS AFTER HYDROCHLORIDE SEROTONIN DESTRUCTIVE IMPACT AND THE POSSIBILITY OF CORRECTION BY STIMULANTS OF METABOLIC PROCESSES].  |  Brechka, N., et al. 2015. Fiziol Zh (1994). 61: 85-91. PMID: 26552310
  10. Detailed chemical characterization and molecular modeling of serotonin inclusion complex with unmodified β-cyclodextrin.  |  Fateminasab, F., et al. 2019. Heliyon. 5: e01405. PMID: 31008382
  11. Uptake and release characteristics of serotonin hydrochloride by natural Cuban zeolite containing clinoptilolite and mordenite.  |  Grass, JP., et al. 2021. Sci Rep. 11: 14277. PMID: 34253745
  12. Influences of Serotonin Hydrochloride on Adiponectin, Ghrelin and KiSS1 Genes Expression.  |  Mahmoudi, F. and Haghighat Gollo, K. 2020. Galen Med J. 9: e1767. PMID: 34466589
  13. Serotonin as a neurotransmitter in cerebral arteries.  |  Griffith, SG., et al. 1982. Brain Res. 247: 388-92. PMID: 6127149

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Serotonin hydrochloride, 100 mg

sc-201146
100 mg
$116.00

Serotonin hydrochloride, 1 g

sc-201146A
1 g
$183.00

could I please get some price and estimated delivery time for this product, thank you

Asked by: Heike
To obtain accurate availability, shipping and pricing information, please contact our local distributor in New Zealand. You can find their information here: https://www.scbt.com/scbt/resources/distributors.
Answered by: Tech Service
Date published: 2018-11-21
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Rated 5 out of 5 by from Perrier et alPerrier et al. (PubMed ID 18096602) used serotonin hydrochloride to perform microiontophoresis experiments to study motoneuron membrane stability. -SCBT Publication Review
Date published: 2015-06-14
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Serotonin hydrochloride is rated 5.0 out of 5 by 1.
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