GAGE10 Inhibitors
"G antigen 10," also known as GAGE10, is a member of the G antigen family, a group of proteins predominantly expressed in germ cells and various cancers. GAGE10 is encoded by the GAGE10 gene located on chromosome Xq28. This protein belongs to the cancer/testis antigen (CTA) group, characterized by their restricted expression pattern in normal tissues and aberrant expression in various cancers, including melanoma, lung cancer, and sarcomas.GAGE10 plays a significant role in tumorigenesis and cancer progression. While its exact function remains largely elusive, studies suggest its involvement in cellular processes such as cell cycle regulation, apoptosis, and transcriptional regulation. GAGE10 expression is tightly regulated and predominantly restricted to male germ cells in normal physiological conditions. However, aberrant expression in cancer cells is attributed to epigenetic changes, such as DNA hypomethylation and histone modifications, leading to its reactivation in cancerous tissues.
GAGE10 expression has been explored as a potential biomarker for cancer diagnosis and prognosis. Challenges remain in fully elucidating the biological functions of GAGE10. Further research into the molecular mechanisms underlying GAGE10 expression and its role in cancer biology is warranted to harness its full potential in cancer diagnosis.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may inhibit G antigen 10 expression by modulating key signaling pathways involved in its transcriptional regulation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has the potential to inhibit G antigen 10 expression, possibly through its action on epigenetic regulatory mechanisms. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin could inhibit G antigen 10 expression by interfering with its transcriptional activation through specific signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG may inhibit G antigen 10 expression by modulating epigenetic modifications or transcription factor activity. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $32.00 $42.00 $162.00 $292.00 | 12 | |
Baicalein might inhibit G antigen 10 expression by interfering with its transcriptional regulation via various cellular pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein may inhibit G antigen 10 expression by modulating signaling cascades involved in its transcriptional regulation. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin could inhibit G antigen 10 expression by interfering with its transcriptional activation through specific cellular pathways. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine has the potential to inhibit G antigen 10 expression by modulating key signaling pathways involved in its transcription. | ||||||
Gingerol | 23513-14-6 | sc-201519 sc-201519A | 5 mg 20 mg | $109.00 $387.00 | 5 | |
Gingerol may inhibit G antigen 10 expression by interfering with its transcriptional regulation through modulation of signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane could inhibit G antigen 10 expression through modulation of epigenetic mechanisms or interference with transcription factors. | ||||||