Date published: 2026-6-6

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Fringe Antibodies

Santa Cruz Biotechnology features a diverse variety of Fringe Antibodies for studying the Fringe protein family, which plays a crucial role in the regulation of Notch signaling pathways. Fringe Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Fringe proteins modulate the activity of Notch receptors, influencing cell fate determination, differentiation, and tissue development. Understanding Fringe protein function is essential for developmental biology research and has significant implications for cancer studies. Researchers can investigate specific protein expression patterns and cellular localization using advanced visualization methods. Fringe protein research continues to reveal new insights about cellular communication networks and developmental processes. The relationship between Fringe proteins and Notch signaling opens new possibilities for therapeutic interventions. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of fundamental biological mechanisms and potential therapeutic applications.

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Fringe Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Lunatic Fringe Antibody (TT-07)

sc-100756mouse IgG2a κ1-251 (h)WB, IP, ELISAm, r, h
1
(2)

Manic Fringe Antibody (2B11)

sc-517162mouse IgG2a κ214-291 (h)WB, IP, ELISAh

new

(1)

Radical Fringe Antibody (18-K2)

sc-100754mouse IgG1 κ82-191 (h)WB, IP, IF, ELISAh

new

(3)

Fringe CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Lunatic Fringe CRISPR/Cas9 KO Plasmid (m)

sc-421414mGene KnockoutGFP0
(0)

Radical Fringe CRISPR/Cas9 KO Plasmid (m)

sc-422659mGene KnockoutGFP0
(0)

Fringe siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Lunatic Fringe siRNA (h)

sc-39490hGene SilencingN/A0
(0)

Lunatic Fringe shRNA Plasmid (h)

sc-39490-SHhGene SilencingPuromycin0
(0)

Lunatic Fringe shRNA (h) Lentiviral Particles

sc-39490-VhGene SilencingPuromycin0
(0)

Lunatic Fringe siRNA (m)

sc-39491mGene SilencingN/A
1
(0)

Lunatic Fringe shRNA Plasmid (m)

sc-39491-SHmGene SilencingPuromycin
1
(0)

Lunatic Fringe shRNA (m) Lentiviral Particles

sc-39491-VmGene SilencingPuromycin
1
(0)

Manic Fringe siRNA (h)

sc-39492hGene SilencingN/A0
(0)

Manic Fringe shRNA Plasmid (h)

sc-39492-SHhGene SilencingPuromycin0
(0)

Manic Fringe shRNA (h) Lentiviral Particles

sc-39492-VhGene SilencingPuromycin0
(0)

Manic Fringe siRNA (m)

sc-39493mGene SilencingN/A
1
(0)

Manic Fringe shRNA Plasmid (m)

sc-39493-SHmGene SilencingPuromycin
1
(0)

Manic Fringe shRNA (m) Lentiviral Particles

sc-39493-VmGene SilencingPuromycin
1
(0)

Radical Fringe siRNA (h)

sc-39494hGene SilencingN/A0
(0)

Radical Fringe shRNA Plasmid (h)

sc-39494-SHhGene SilencingPuromycin0
(0)

Radical Fringe shRNA (h) Lentiviral Particles

sc-39494-VhGene SilencingPuromycin0
(0)

Radical Fringe siRNA (m)

sc-39495mGene SilencingN/A
1
(0)

Radical Fringe shRNA Plasmid (m)

sc-39495-SHmGene SilencingPuromycin
1
(0)

Radical Fringe shRNA (m) Lentiviral Particles

sc-39495-VmGene SilencingPuromycin
1
(0)