Date published: 2026-1-16

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FHDC1 Activators

FHDC1 Activators are a class of chemicals that putatively engage with specific cellular and biochemical pathways to enhance the functional activity of FHDC1. These compounds interact with various signaling molecules, enzymes, and receptors to initiate a cascade of events that may lead to the activation of FHDC1. For instance, agents like Phorbol 12-myristate 13-acetate (PMA) could potentiate FHDC1 by activating protein kinase C, which might phosphorylate and thus modulate FHDC1's activity. Forskolin, by increasing intracellular cAMP levels, activates PKC.

Insulin is pivotal in activating the insulin receptor signaling pathway, incorporating the PI3K-Akt pathway. In the event that FHDC1 is an integrant or is modulated by this pathway, the presence of insulin could enhance the activity of FHDC1. Ionomycin, a calcium ionophore, serves to elevate intracellular calcium levels, which in turn can activate calcium-sensitive proteins. If FHDC1 is controlled by calcium-mediated signaling, ionomycin may be capable of boosting its activity.Isoproterenol, a β-adrenergic agonist, stimulates adenylyl cyclase, leading to increased cAMP levels and PKA activation. Should β-adrenergic pathways influence FHDC1, isoproterenol could be effective in magnifying FHDC1's action.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C (PKC), which is involved in numerous signaling pathways. If FHDC1 is regulated by PKC through phosphorylation, PMA could enhance FHDC1 activity by activating PKC.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylyl cyclase, increasing cAMP levels, and can activate PKA. If FHDC1 activity is modulated by PKA phosphorylation, forskolin can enhance FHDC1 function indirectly through this pathway.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin activates the insulin receptor signaling pathway, which includes the PI3K-Akt pathway. If FHDC1 is part of this pathway or regulated by it, insulin can enhance FHDC1 function.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Ionomycin is a calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent proteins. If FHDC1 is regulated by calcium signaling, ionomycin could enhance its activity.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

Isoproterenol is a β-adrenergic agonist that activates adenylyl cyclase, raising cAMP levels and activating PKA. If FHDC1 is influenced by β-adrenergic signaling, isoproterenol can enhance its activity.

(±)-S-Nitroso-N-acetylpenicillamine

79032-48-7sc-200319B
sc-200319
sc-200319A
10 mg
20 mg
100 mg
$74.00
$114.00
$374.00
18
(3)

Nitric oxide donors release NO, which can activate guanylyl cyclase and increase cGMP levels. If FHDC1 is modulated by cGMP-dependent protein kinases, this could enhance FHDC1 activity.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride inhibits GSK-3, a negative regulator of the Wnt signaling pathway. If FHDC1 is regulated by Wnt signaling components, lithium chloride can enhance FHDC1 indirectly.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid regulates gene expression through retinoic acid receptors. If FHDC1 is regulated at a transcriptional level by retinoic acid, its functional activity could be enhanced.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

Estrogen binds to estrogen receptors and can modulate gene expression. If FHDC1 is estrogen-responsive, estrogen can enhance its activity.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$47.00
$136.00
$492.00
$4552.00
74
(7)

Dibutyryl cAMP is a membrane-permeable analogue of cAMP that activates PKA. If FHDC1 is modulated by PKA, this compound can enhance its activity.