FGFR Inhibitors
Santa Cruz Biotechnology now offers a broad range of FGFR Inhibitors. Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. FGFR Inhibitors offered by Santa Cruz inhibit FGFR and, in some cases, other cell proliferation and growth factor related proteins. View detailed FGFR Inhibitor specifications, including FGFR Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 1 to 10 of 14 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SU 6668 | 252916-29-3 | sc-204309 sc-204309A | 10 mg 50 mg | $127.00 $712.00 | 2 | |
SU 6668 (CAS 252916-29-3) is a synthetic small molecule known for its role as an FGFR inhibitor. It exerts its inhibitory action by targeting the ATP-binding site within FGFRs, impeding their autophosphorylation and subsequent downstream signaling. This disruption interferes with cellular processes involved in growth, differentiation, and survival. | ||||||
Erdafitinib | 1346242-81-6 | sc-507388 | 10 mg | $138.00 | ||
Erdafitinib is a tyrosine kinase inhibitor that targets FGFR1. | ||||||
BGJ398 | 872511-34-7 | sc-364430 sc-364430A sc-364430B sc-364430C | 5 mg 10 mg 50 mg 100 mg | $212.00 $247.00 $582.00 $989.00 | 4 | |
Infigratinib is an FGFR-selective tyrosine kinase inhibitor. | ||||||
AP 24534 | 943319-70-8 | sc-362710 sc-362710A | 10 mg 50 mg | $172.00 $964.00 | 2 | |
AP 24534 (CAS 943319-70-8) functions as an FGFR inhibitor. By targeting the ATP-binding domain of FGFR, it impedes receptor autophosphorylation, disrupting downstream signaling cascades involved in critical cellular processes such as proliferation and differentiation. | ||||||
PD 161570 | 192705-80-9 | sc-361284 sc-361284A | 5 mg 25 mg | $112.00 $446.00 | 1 | |
PD 161570 (CAS 192705-80-9) operates as an FGFR inhibitor by competitively binding to the ATP-binding pocket within FGFRs. This impedes receptor autophosphorylation and subsequent intracellular signaling pathways vital for cellular functions like proliferation and differentiation. | ||||||
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 | sc-222143 | 5 mg | $326.00 | |||
The chemical "PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668" acts as an FGFR inhibitor by obstructing the ATP-binding site in FGFRs. This curtails receptor autophosphorylation, disrupting downstream signaling that regulates pivotal cellular functions like growth and differentiation. | ||||||
FGF Receptor Tyrosine Kinase Inhibitor | 192705-79-6 | sc-221612 | 5 mg | $287.00 | ||
The chemical (CAS 192705-79-6) is an FGFR inhibitor that hinders the receptor's tyrosine kinase activity. By binding to the ATP-binding domain, it disrupts autophosphorylation and subsequent cellular signaling, affecting processes such as growth and differentiation. | ||||||
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 | 210644-62-5 | sc-204175 | 5 mg | $79.00 | 9 | |
The compound with CAS 210644-62-5, known as "PDGFR Tyrosine Kinase Inhibitor VI, SU6668," functions as an FGFR inhibitor. It hampers receptor activity by targeting the ATP-binding site, restraining autophosphorylation and downstream cellular signaling involved in growth and differentiation. | ||||||
SU 5402 | 215543-92-3 | sc-204308 sc-204308A | 1 mg 5 mg | $62.00 $96.00 | 36 | |
SU 5402 (CAS 215543-92-3) is recognized as an FGFR inhibitor. It acts by binding to the ATP-binding pocket of FGFR, hampering autophosphorylation and downstream signaling processes responsible for cell growth and differentiation. | ||||||
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 | sc-221613 | 5 mg | $220.00 | |||
"FGF Receptor Tyrosine Kinase Inhibitor IV, NP603" is a compound that inhibits FGFR activity. By targeting the ATP-binding site, it disrupts autophosphorylation, interfering with downstream cellular signaling linked to growth and differentiation processes. | ||||||