Molecular structure of PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668
Alternate Names:
(Z)-3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl-5-bromo)-1H-pyrrol-3-yl)-propionic acid
Application:
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is a potent PDGFR, VEGFR2, and FGFR1 inhibitor
Molecular Weight:
389.2
Molecular Formula:
C18H17BrN2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is a cell-permeable, ATP-binding pocket-targeting, 5-bromoindolinone analog of SU6668. PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is equally potent as SU6668 in inhibiting PDGFR, while increasing activity against VEGFR2 and FGFR1 in cell-free kinase assays. Inhibits cell proliferation mediated by VEGF, FGF, and PDGFβ. Little effect against EGF-mediated cell proliferation or EGFR in vitro kinase activity.
Inhibitor of:
FGFR, Flg, Flk-1, and PDGFR-beta.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668, 5 mg | sc-222143 | 5 mg | $333.00 |