The chemical class known as Fc ε RIγ inhibitors encompasses a diverse group of compounds meticulously designed to modulate the activity of Fc epsilon receptor I gamma chain (Fc ε RIγ), a protein crucially involved in immune responses and allergic reactions. These inhibitors are developed through an intricate interplay of structural insights and mechanistic studies, often utilizing advanced techniques such as computational modeling, high-throughput screening, and chemical synthesis. The primary objective is to engineer compounds with precise capabilities to selectively interact with Fc ε RIγ, potentially influencing its role in immune signaling and cellular responses.
By targeting Fc ε RIγ, these inhibitors provide essential tools for probing the complex mechanisms that govern allergic reactions and immune modulation, shedding light on the intricate processes that underlie immune cell activation and sensitization. The exploration of Fc ε RIγ inhibitors contributes to a deeper understanding of the finely tuned interactions within immune pathways, revealing insights into the nuanced dynamics that regulate immune responses and the intricate orchestration of cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Piceatannol | 10083-24-6 | sc-200610 sc-200610A sc-200610B | 1 mg 5 mg 25 mg | $51.00 $71.00 $199.00 | 11 | |
A natural polyphenol, piceatannol has been studied for its potential inhibitory effects on Fc ε RIγ-mediated signaling and its impact on allergic responses. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
Derived from Garcinia indica fruit, garcinol has been explored for its interactions with Fc ε RIγ and its potential role in modulating immune responses. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Another natural flavonoid, fisetin has been investigated for its effects on Fc ε RIγ-mediated signaling and its potential implications for allergic reactions. | ||||||
Masitinib | 790299-79-5 | sc-211777 | 10 mg | $184.00 | ||
An experimental drug, masitinib has been studied for its potential inhibitory effects on Fc ε RIγ-mediated responses and its impact on immune modulation. | ||||||
CCG 203971 | 1443437-74-8 | sc-507360 | 10 mg | $89.00 | ||
This compound has been explored for its potential inhibitory effects on Fc ε RIγ signaling and its implications for immune responses. | ||||||
Baicalin | 21967-41-9 | sc-204638 sc-204638A sc-204638B sc-204638C | 1 mg 25 mg 1 g 5 g | $56.00 $112.00 $224.00 $265.00 | 4 | |
A flavonoid compound, baicalin has been investigated for its interactions with Fc ε RIγ and its potential role in modulating allergic reactions. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Another flavonoid, luteolin has been studied for its potential inhibitory effects on Fc ε RIγ-mediated signaling and its impact on immune responses. | ||||||
Glabridin | 59870-68-7 | sc-397145 sc-397145A | 5 mg 25 mg | $133.00 $530.00 | ||
Derived from licorice root, glabridin has been explored for its interactions with Fc ε RIγ and its potential role in modulating allergic responses. | ||||||
R788 | 901119-35-5 | sc-364597 sc-364597A | 2 mg 50 mg | $405.00 $4000.00 | 2 | |
An experimental drug, R788 has been studied for its potential inhibitory effects on Fc ε RIγ-mediated responses and its impact on immune modulation. | ||||||
Tanshinone IIA | 568-72-9 | sc-200932 sc-200932A | 5 mg 25 mg | $88.00 $316.00 | 22 | |
Derived from Danshen root, tanshinone IIA has been investigated for its effects on Fc ε RIγ-mediated signaling and its potential implications for allergic reactions. | ||||||