Baicalin CAS: 21967-41-9
MF: C21H18O11
MW: 446.37
A flavonoid compound with antioxidant effects.

Baicalin (CAS 21967-41-9)

Baicalin | CAS 21967-41-9 is rated 5.0 out of 5 by 1.
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Application: Baicalin is a flavonoid compound with antioxidant effects
CAS Number: 21967-41-9
Purity: ≥95%
Molecular Weight: 446.37
Molecular Formula: C21H18O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Baicalin is a flavonoid compound with anti-inflammatory and anti-oxidant activity extracted from Scutellarua rivularis. HIV studies show that Baicalin inhibits HIV-1 replication by blocking the activity of the reverse transcriptase (HIV-1 RT). Baicalin has been suggested by Neural Stem cell studies to act as a strong inducer of neural differentiation by activating Erk1/2. Additionally, Baicalin was reported to inhibit the up-regulation of the connective tissue growth factor, and blocks the TLR2/4 signaling pathway. Baicalin is an inhibitor of PREP.


References

1. Lin, C.C. and Shieh, D.E. 1996. Am. J. Chin. Med. 24: 31-36. PMID: 8739179
2. Kitamura, K., et al. 1998. Antiviral Res. 37: 131-140. PMID: 9588845
3. Tu, X.K., et al. 2010. Inflammation. PMID: 20859668
4. Jia, H., et al. 2010. Sheng Li Xue Bao. 62: 535-540. PMID: 21170500
5. Li, M., et al. 2011. Chembiochem. [Epub ahead of print]. PMID: 21207428

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (<1 mg/ml at 25° C), DMF, DMSO (89 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
Storage :
Store at -20° C
Melting Point :
202-205° C (lit.)(dec.)
Boiling Point :
836.62° C at 760 mmHg (Predicted)
Density :
1.74 g/cm3
Refractive Index :
n20D 1.74
Optical Activity :
α20/D -85°, c = 1 in DMSO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
LZ5776910
PubChem CID :
MDL Number :
MFCD00134418
SMILES :
C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O

Download SDS (MSDS)

Certificate of Analysis

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Baicalin (CAS 21967-41-9)  Product Citations

See how others have used Baicalin (CAS 21967-41-9). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 32774702  Am J Transl Res. 3311-3328.

PMID: # 33190590  Cell Cycle. 1-19.

PMID: # 29445081  Cell Death Dis. 9: 234.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from Jia et al Jia et al. (PubMed ID 21170500) found that Baicalin could reduce CTGF expression in fibrotic lungs of rats. -SCBT Publication Review
Date published: 2015-05-26
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