FBL15 activators belong to a class of chemicals that interact with the cellular protein known as FBL15, which is a part of the larger family of proteins playing critical roles in various cellular processes. These activators are specifically designed to modulate the activity of FBL15, which can have multiple effects on cellular functions. The biochemical interaction between FBL15 activators and their target protein often involves the binding of these molecules to specific sites on the FBL15 protein, leading to a change in its conformation and subsequent alteration in its activity. This modulation can either enhance or inhibit the protein's function, depending on the nature of the activator and the context of its application. The precise mechanism of action of these activators is usually the subject of intense research as it requires a detailed understanding of the protein's structure, the binding affinity of the activators, and the downstream effects of such activation on cellular pathways.
The development and study of FBL15 activators are grounded in the pursuit of understanding fundamental biological mechanisms. The interactions between FBL15 and its activators can illuminate the role of this protein in cellular biology, such as its involvement in the regulation of protein synthesis, its impact on the cell cycle, or its influence on the maintenance of cellular homeostasis. By focusing on the biochemical and molecular properties of these activators, researchers aim to unravel the complexities of protein function within the cell. The specificity of these activators is of particular interest, as it provides insights into how small molecules can selectively interact with targeted proteins amidst the vast array of biomolecules within a cell. Moreover, the study of FBL15 activators encompasses a variety of disciplines, including organic chemistry for the synthesis of the molecules, biochemistry for understanding the interaction with the protein, and molecular biology for observing the subsequent effects on cellular processes. Thus, FBL15 activators serve as valuable tools for probing the intricate web of cellular protein functions.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
A potent and selective inhibitor of protein kinase C (PKC). FBL15's function is influenced by PKC activity. By inhibiting PKC, Bisindolylmaleimide I can lead to the compensatory activation of alternative pathways that enhance the functional activity of FBL15. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Direct activator of PKC. PMA activates PKC, which in turn could upregulate downstream pathways that FBL15 is involved in, leading to enhanced activity of FBL15. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, Forskolin raises intracellular cyclic AMP (cAMP) levels, which can lead to the activation of PKA. PKA activation may result in phosphorylation events that enhance the activity of FBL15. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
A potent inhibitor of protein phosphatases PP1 and PP2A, Okadaic Acid indirectly increases phosphorylation levels in cells, which could enhance the functional activity of FBL15 through increased phosphorylation-dependent signaling pathways. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
A calcium ionophore which increases intracellular calcium levels. Elevated calcium can activate calmodulin-dependent kinases, potentially increasing the functional activity of FBL15 via calcium-dependent signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea, EGCG has been shown to inhibit several protein kinases, potentially altering signaling pathways that indirectly lead to the functional activation of FBL15. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A specific inhibitor of phosphoinositide 3-kinases (PI3K). By inhibiting PI3K, LY294002 may shift the signaling balance to pathways that enhance the activity of FBL15. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Another calcium ionophore, A23187 increases intracellular calcium levels, which could enhance the functional activity of FBL15 through calcium-dependent signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A specific and irreversible inhibitor of PI3K. Similar to LY294002, Wortmannin may influence pathways that enhance the functional activity of FBL15 by shifting signaling dynamics. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A specific inhibitor of p38 MAP kinase. Inhibition of p38 may lead to the activation of alternative pathways or reduce negative feedback loops, thus enhancing the activity of FBL15. | ||||||