FAT1 Activators
The collection of chemicals classified as FAT1 Activators predominantly revolves around compounds with the capacity to modulate key cellular signaling pathways, which can then indirectly influence the FAT1 protein. Within this realm, Wnt3a and Lithium chloride stand out for their potential to activate the Wnt/β-catenin signaling pathway, a route that has intersections with FAT1's involvement in cellular adhesion and planar cell polarity. Another noteworthy compound is EGF, which, by instigating the EGF receptor pathway, might establish interactions with FAT1-mediated processes.
Additionally, compounds such as Forskolin play significant roles in cellular functions like proliferation, differentiation, and the modulation of intracellular cAMP levels. Their relevance arises from the possibility of influencing pathways or cellular dynamics that FAT1 participates in. The presence of agents like Isoproterenol, PMA, LY294002, Y-27632, and PD98059 further diversifies the landscape, introducing modulators of PKC, PI3K/AKT, ROCK, and MAPK/ERK pathways, respectively.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Activates Wnt signaling, potentially modulating FAT1's role in planar cell polarity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases intracellular cAMP levels, potentially influencing FAT1 activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
β-adrenergic receptor agonist that might modulate cAMP pathways intersecting with FAT1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates Protein Kinase C (PKC) which can influence pathways that FAT1 operates in. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor; by modulating the PI3K/AKT pathway, it can affect processes potentially associated with FAT1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor; impacts the MAPK/ERK pathway, which may have intersections with FAT1 processes. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Cyclin-dependent kinase inhibitor that can affect cell cycle and differentiation processes, potentially influencing FAT1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor; affects cellular growth and proliferation pathways that might have intersections with FAT1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor, influencing the PI3K/AKT signaling pathway which can have a role in processes associated with FAT1. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
A calcium ionophore that can elevate intracellular calcium levels, potentially influencing signaling pathways and cellular processes associated with FAT1. | ||||||