FANCC Activators
Activators of FANCC are varied in their structure and operation, yet they share the common attribute of strengthening the DNA repair pathways to which FANCC is essential. Elements that act as cofactors for enzymes critical to the DNA repair process play an important role, ensuring that FANCC operates at peak efficiency. Likewise, certain botanical compounds activate cellular pathways that boost the expression and function of FANCC, particularly in response to genetic damage. Other plant-based molecules enhance specific repair mechanisms, like homologous recombination, where FANCC is crucial, through their interaction with various cellular signaling pathways, contributing to the stabilization of proteins and inhibition of certain kinases, potentially leading to improved DNA repair processes involving FANCC.
In addition, certain bioactive compounds stimulate signaling pathways that enhance the expression of genes involved in cellular defense or activate DNA damage checkpoints, indirectly boosting the necessity for FANCC's repair activities. Precursors necessary for the synthesis of critical cofactors for DNA repair enzymes provide vital support, thereby aiding in the optimal function of FANCC. Some agents induce a cellular stress response that sets off a series of DNA damage responses, including those in which FANCC plays a part, thereby indirectly raising its activity levels. Others indirectly affect the machinery by altering gene expression related to DNA repair, lending support to the array of FANCC functions.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound that activates the NF-kB pathway, known to be involved in the regulation of DNA repair and apoptosis. Activation of NF-kB by curcumin would enhance the expression and function of FANCC, which is crucial for the DNA repair process. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Sirtuin activator that influences the DNA damage response by deacetylating proteins involved in repair mechanisms. Through the activation of sirtuins, resveratrol promotes the homologous recombination process in which FANCC plays a vital role. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
An inducer of antioxidant response elements (ARE) via the Nrf2 signaling pathway. By upregulating the expression of genes associated with cellular defense mechanisms, this compound indirectly supports the function of FANCC in maintaining genomic stability. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol that modulates the ATM/ATR pathway crucial for cell cycle control and DNA repair. Its role in enhancing the repair pathway indirectly bolsters FANCC’s activity in response to DNA damage. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Flavonoid that stabilizes p53, a protein that regulates the cell cycle and thus influences DNA repair processes. Quercetin's effect on p53 can enhance the DNA repair machinery, indirectly promoting FANCC’s role within it. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Isoflavone that inhibits protein tyrosine kinases, affecting multiple signaling pathways, including those involved in DNA damage response. This inhibition can result in the activation of pathways where FANCC is a key player. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential metal ion that serves as a cofactor for many DNA repair enzymes. Zinc’s presence is critical for the proper function of the DNA repair machinery, and thus it is vital for the optimal activity of FANCC. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
A secosteroid that modulates various cellular processes, including DNA repair and apoptosis. It influences the expression of genes involved in DNA damage response, thereby indirectly supporting FANCC function. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A polyphenol that activates the DNA damage checkpoint, leading to cell cycle arrest and DNA repair. Through this activation, ellagic acid can enhance the function of FANCC involved in the repair process. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
A form of vitamin B3 that acts as a precursor for NAD+, which is essential for PARP enzymes involved in DNA repair. By supporting PARP activity, nicotinamide indirectly facilitates the function of FANCC in the DNA damage response. | ||||||