FAM174B Activators
FAM174B Activators are a group of chemical compounds that indirectly augment the functional activity of FAM174B through various signaling pathways. Compounds like Forskolin and Dibutyryl-cAMP elevate intracellular cAMP levels, which in turn activate Protein Kinase A (PKA). This activation can lead to the phosphorylation of downstream targets that may indirectly enhance the activity of FAM174B through cAMP-dependent pathways. Similarly, Biochanin A, by inhibiting tyrosine kinases, and Epigallocatechin gallate (EGCG), by its effects on multiple kinases, could modify the signaling landscape in a way that indirectly enhances the activity of FAM174B. The use of Sphingosine-1-phosphate, which acts on sphingosine-1-phosphate receptors, and LY294002, a PI3K inhibitor, could lead to changes in PI3K/Akt signaling, potentially enhancing FAM174B activity.
Moreover, the modulation of MAPK signaling through the use of U0126, which inhibits MEK1/2, and SB203580, a p38 MAPK inhibitor, could shift the cellular signaling balance to indirectly enhance the activity of FAM174B. Ionomycin and A23187 (Calcimycin), by increasing intracellular calcium concentrations, activate calcium-dependent signaling pathways, potentially affecting the activity of FAM174B. Additionally, Thapsigargin disrupts calcium homeostasis by inhibiting the SERCA pump, leading to increased cytosolic calcium levels, which may indirectly enhance FAM174B activity through calcium signaling. Phorbol 12-myristate 13-acetate (PMA) activates Protein Kinase C (PKC), a signaling molecule involved in various pathways, which can lead to an enhancement of FAM174B's activity through PKC-dependent signaling. Collectively, these FAM174B Activators, by targeting specific signaling mechanisms, facilitate the indirect enhancement of FAM174B-mediated functions without directly increasing its expression or binding to the protein itself.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates Protein Kinase C (PKC) which is involved in many signaling pathways. PKC activation can lead to the phosphorylation of proteins and alter signaling cascades that may indirectly enhance the activity of FAM174B. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Acts as a ligand for sphingosine-1-phosphate receptors, which can activate intracellular signaling pathways such as PI3K/Akt, potentially influencing cellular processes that could enhance the activity of FAM174B. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium concentration, which can activate calcium-dependent signaling pathways. These pathways can lead to the activation of proteins which may enhance the activity of FAM174B. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenolic compound that has multiple effects on cellular signaling, including inhibition of certain protein kinases, which could lead to an indirect enhancement of FAM174B activity by altering the cellular signaling landscape. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A specific inhibitor of PI3K, which can alter the PI3K/Akt pathway. This modulation could lead to compensatory signaling changes that indirectly enhance the activity of FAM174B. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Inhibits MEK1/2, leading to decreased MAPK/ERK pathway signaling. This could shift the balance of cellular signaling in a way that indirectly enhances the activity of FAM174B. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor that can alter p38-dependent signaling pathways, potentially enhancing the activity of FAM174B indirectly by affecting downstream signaling proteins. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Increases intracellular calcium concentration and activates calcium-dependent signaling pathways, which could indirectly enhance the activity of FAM174B by modifying calcium signaling. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
A SERCA pump inhibitor that leads to increased cytosolic calcium levels, potentially enhancing FAM174B activity through calcium-dependent signaling pathways. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A cell-permeable cAMP analog that activates PKA and can mimic the effects of cAMP in cells, potentially leading to enhanced FAM174B activity through cAMP-dependent signaling pathways. | ||||||