FAM160B1 Activators encompass a diverse array of chemical compounds that indirectly stimulate the functional activity of FAM160B1 through multiple signaling pathways. Forskolin and Dibutyryl-cAMP, by increasing intracellular cAMP levels, activate PKA, which can phosphorylate proteins and substrates that may interact with FAM160B1, thus potentially enhancing its function. Similarly, Ionomycin and Thapsigargin elevate intracellular calcium levels, activating calcium-dependent pathways that could intersect with FAM160B1 activity. PMA, as a PKC activator, and Epigallocatechin gallate, through kinase inhibition, may modulate signaling environments conducive to FAM160B1 activation by influencing pathways that the protein engages with. Additionally, the introduction of Insulin into the cellular environment triggers PI3K/Akt signaling, which could have downstream effects on FAM160B1 activity if the protein is tied to this pathway.
Furthermore,the inclusion of LY294002, a PI3K inhibitor, alters Akt signaling dynamics, which could have implications for FAM160B1 activity if PI3K/Akt signaling impacts the protein. Okadaic acid's inhibition of protein phosphatases such as PP1 and PP2A leads to heightened phosphorylation states within the cell, which could result in the indirect activation of FAM160B1 through phosphorylation-dependent mechanisms. Similarly, Staurosporine, despite its broad inhibitory effects on kinases, may selectively modulate pathways that affect FAM160B1 activity. Sphingosine-1-phosphate acts through its receptors to initiate signaling that could engage FAM160B1, while Anisomycin induces a stress response that activates JNK and p38 MAPK pathways, potentially altering the signaling landscape in a manner that indirectly augments FAM160B1 activity. Collectively, these activators work through distinct mechanisms to influence the cellular signaling milieu, thereby enhancing the activity of FAM160B1 without directly targeting the protein or its expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium concentrations. This rise in calcium can activate calcium-dependent signaling cascades, which may indirectly enhance the activity of FAM160B1 by modulating calcium-sensitive pathways that interact with the protein. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is an activator of protein kinase C (PKC). PKC plays a role in several signaling pathways and can phosphorylate targets that might be involved with FAM160B1 function, indirectly enhancing the protein's activity. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the PI3K/Akt signaling pathway, which is involved in a wide array of cellular functions. Activation of this pathway could indirectly enhance FAM160B1 activity if the protein is part of cellular processes modulated by PI3K/Akt. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is known to inhibit certain types of kinases. By inhibiting competitive kinases, it could shift signaling dynamics in favor of pathways that interact with or activate FAM160B1, thereby enhancing its functional activity. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
db-cAMP is a cell-permeable cAMP analog that activates PKA. By activating PKA, db-cAMP could phosphorylate substrates that interact with or modulate FAM160B1 function, enhancing the protein’s activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that leads to an increase in cytosolic calcium levels, potentially activating calcium-dependent proteins and pathways that might influence FAM160B1 activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, leading to increased phosphorylation levels in the cell. This could indirectly activate FAM160B1 if it is regulated by phosphorylation events. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P acts on its receptors to activate intracellular signaling pathways, including those involved in cytoskeletal rearrangement. Such pathways could interact with or activate FAM160B1, enhancing its activity. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a protein synthesis inhibitor that activates stress-activated protein kinases, such as JNK and p38 MAPK. This stress response could indirectly affect FAM160B1 activity by modulating related signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that could modulate downstream Akt signaling. This alteration in signaling could indirectly influence FAM160B1 activity if the protein is affected by the PI3K/Akt pathway. | ||||||