FAM124B Activators
FAM124B activators are a category of chemical compounds that have been shown to indirectly influence the activity of FAM124B through the modulation of either mitochondrial function or nucleoplasmic activity. Chemicals like Metformin, Resveratrol, and Quercetin are known for their capability to enhance mitochondrial activity through AMPK pathway activation, SIRT1 activation, and NRF2 pathway influence, respectively. Such modulation of mitochondrial function is critical given the FAM124B protein's mitochondrial localization, making these activators key players in its upregulation.
On the other hand, Forskolin and Retinoic Acid function in a different domain. Forskolin activates adenylate cyclase, thus increasing cAMP levels, a nucleoplasmic activity that can upregulate FAM124B. Retinoic Acid is involved in gene expression regulation within the nucleoplasm, providing another layer of control. These chemicals represent different facets of cellular control that can intersect with FAM124B function, either through mitochondrial enhancement or through nucleoplasmic activity modulation, to achieve its activation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Activates AMPK pathway, which enhances mitochondrial activity. The enhanced mitochondrial function can indirectly increase the activity of FAM124B. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Activates SIRT1, which plays a role in mitochondrial biogenesis. This can indirectly increase FAM124B activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Influences NRF2 pathway that controls mitochondrial biogenesis, which can upregulate FAM124B. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AMPK activator that improves mitochondrial function, indirectly enhancing FAM124B activity. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
NAD+ precursor that can enhance mitochondrial function, indirectly impacting FAM124B. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences PI3K/Akt pathway which is known to have an effect on mitochondrial activity, potentially activating FAM124B. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Induces autophagy, which includes mitochondrial renewal, possibly impacting FAM124B. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Activates Nrf2 pathway, which may enhance mitochondrial function and indirectly increase FAM124B. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression in the nucleoplasm, possibly affecting FAM124B. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Affects PGC-1α, a regulator of mitochondrial biogenesis, potentially activating FAM124B. | ||||||