FAM101B Inhibitors
FAM101B kinase inhibitors like Staurosporine have the potential to affect the phosphorylation state of numerous proteins. If FAM101B were subject to regulation by phosphorylation, this compound could alter its activity. Similarly, Thapsigargin, by perturbing calcium homeostasis, could indirectly affect proteins that are sensitive to calcium signaling. Bafilomycin A1 and Tunicamycin might interfere with protein sorting or post-translational modifications of FAM101B, respectively. Cyclosporin A, through the inhibition of calcineurin, could alter FAM101B function if it is modulated by dephosphorylation processes.
Compounds like U0126 and SB203580 might modulate FAM101B function by targeting the MAPK signaling cascade, which is a common pathway involved in the regulation of gene expression, cell division, and differentiation. LY294002 and Rapamycin could exert their effects on FAM101B function by acting on the PI3K/AKT/mTOR pathway, a central route for cell growth and metabolism. MG132 might stabilize FAM101B by inhibiting its proteasomal degradation, while 2-Deoxyglucose could impact FAM101B if it has a role in energy-dependent cellular processes. Z-VAD-FMK could alter the apoptotic pathways, which might affect FAM101B if it is involved in cell death regulation.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can affect various signaling pathways; may alter FAM101B function if it is regulated through phosphorylation by specific kinases. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Inhibitor of the sarco/endoplasmic reticulum Ca²⁺-ATPase (SERCA); could impact calcium homeostasis, potentially affecting FAM101B if involved in such pathways. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Specifically inhibits V-ATPase; could disrupt endosomal-lysosomal acidification, which may influence FAM101B function if it relies on lysosomal degradation. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Inhibitor of N-linked glycosylation; may affect FAM101B if it undergoes glycosylation for its stability or function. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Inhibits calcineurin, potentially affecting FAM101B if its function is modulated by Ca²⁺/calmodulin-dependent processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, which may affect stress response pathways potentially linked with FAM101B's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibitor of PI3K, which could reduce the activity of downstream signaling pathways involving FAM101B. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, which could affect protein synthesis and potentially decrease the expression of FAM101B. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can prevent the degradation of proteins, possibly affecting the turnover of FAM101B. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Glycolysis inhibitor that can alter energy metabolism, potentially affecting FAM101B if it is involved in metabolic pathways. | ||||||