EVI2B Activators
EVI2B, or Ecotropic Viral Integration Site 2B, is a gene located on chromosome 17q11.2 in humans, which is associated with the protein product known as EVI2B. The EVI2B gene is situated in a region that is sensitive to insertion by viral elements, an event that can be significant in the onset of certain leukemias due to the disruption of normal gene function.Although the precise role of the EVI2B protein is not fully elucidated, it is postulated to be involved in cellular signaling pathways. The gene is part of a cluster that includes related genes like EVI2A and NGFR, which have been implicated in cell growth, differentiation, and apoptosis, suggesting that EVI2B may have similar biological functions.
EVI2B is expressed in various tissues, with higher expression in immune cells. This pattern suggests a possible role in immune system regulation. Research indicates that the EVI2B gene may influence cell communication and could be involved in the development and function of the nervous system.Given its involvement in growth and signal transduction, EVI2B is an interesting candidate for further research to determine its exact functions and regulatory mechanisms. Understanding EVI2B's role could have implications for our knowledge of cellular processes and the development of diseases, particularly those related to viral integration and oncogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
This compound can mimic cyclic AMP and activate protein kinase A, leading to altered gene expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which may enhance transcription of certain genes. | ||||||
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $75.00 $120.00 | 8 | |
As a retinoid, it can affect gene expression by activating retinoic acid receptors. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Inhibits DNA methyltransferases, potentially leading to gene reactivation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Another retinoid that modulates gene expression through retinoic acid receptor signaling. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A histone deacetylase inhibitor, which can lead to an open chromatin structure and gene activation. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Known to have estrogenic activity, which can influence gene transcription. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A phytoestrogen that can modulate gene expression through interaction with estrogen receptors. | ||||||
Vinclozolin | 50471-44-8 | sc-251425 | 250 mg | $23.00 | 1 | |
A fungicide that acts as an antiandrogen, potentially affecting gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A potent histone deacetylase inhibitor that can alter gene expression patterns. | ||||||