ESAT6 Inhibitors
The chemical class referred to as ESAT6 inhibitors encompasses a diverse group of compounds that have been carefully designed to modulate the activity of ESAT-6 (6-kDa early secretory antigenic target), a protein that holds significant relevance in the pathogenicity of Mycobacterium tuberculosis, the causative agent of tuberculosis. These inhibitors are meticulously developed through an interplay of molecular insights and mechanistic understanding, often employing advanced techniques such as computational modeling, high-throughput screening, and chemical synthesis. The primary aim is to engineer compounds with precision to selectively target ESAT-6, potentially influencing its role in the complex interactions associated with tuberculosis infection.
By targeting ESAT-6, these inhibitors offer invaluable tools for investigating and deciphering the intricate mechanisms that underlie the pathogenesis of tuberculosis, shedding light on the nuanced dynamics that govern the interplay between the pathogen and the host. The exploration of ESAT6 inhibitors contributes to a deeper understanding of the finely orchestrated strategies employed by the pathogen, opening avenues for unraveling the molecular intricacies that influence the course of tuberculosis infection.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A natural compound found in grapes and red wine, resveratrol has been studied for its potential inhibitory effects on ESAT-6 and its impact on TB infection. | ||||||
Thioridazine Hydrochloride | 130-61-0 | sc-201149A sc-201149 sc-201149B sc-201149C sc-201149D | 5 mg 1 g 5 g 25 g 100 g | $20.00 $49.00 $104.00 $416.00 $1248.00 | ||
An antipsychotic agent in research, thioridazine has been investigated for its inhibitory effects on ESAT-6 and its potential role in TB therapy. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound found in turmeric, curcumin has been studied for its potential to inhibit ESAT-6 and modulate TB infection. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $37.00 $146.00 | 3 | |
Another compound from black pepper, piperine has been explored for its potential inhibitory effects on ESAT-6 and its impact on TB pathogenesis. | ||||||
Tanshinone IIA | 568-72-9 | sc-200932 sc-200932A | 5 mg 25 mg | $88.00 $316.00 | 22 | |
An active component of Danshen (Salvia miltiorrhiza), tanshinone IIA has been investigated for its inhibitory effects on ESAT-6 and its role in TB research. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
A flavonoid found in various plants, apigenin has been studied for its potential to inhibit ESAT-6 and its impact on TB infection. | ||||||
Zerumbone | 471-05-6 | sc-364148 sc-364148A | 10 mg 50 mg | $112.00 $408.00 | ||
A natural compound from the ginger family, zerumbone has been investigated for its inhibitory effects on ESAT-6 and its potential impact on TB infection. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Found in green tea, EGCG has been studied for its potential to inhibit ESAT-6 and its role in modulating TB pathogenesis. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A natural polyphenol, ellagic acid has been investigated for its inhibitory effects on ESAT-6 and its role in TB research. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $32.00 $62.00 | 1 | |
Another natural compound, caffeic acid has been studied for its potential to inhibit ESAT-6 and its impact on TB infection. | ||||||