Date published: 2025-10-19

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ERK 1 Inhibitors

ERK 1 inhibitors belong to a specific chemical class of compounds that target the extracellular signal-regulated kinase 1 (ERK 1) enzyme. ERK 1 is a vital component of the mitogen-activated protein kinase (MAPK) signaling pathway, which plays a crucial role in regulating cellular processes such as cell proliferation, differentiation, and survival. The inhibitors are designed to specifically interact with the active site of the ERK 1 enzyme, hindering its activity and subsequent downstream signaling cascades. Chemically, ERK 1 inhibitors are carefully engineered molecules with unique structural features that enable them to bind selectively to the active site of ERK 1, obstructing the phosphorylation of substrate molecules. By impeding the catalytic activity of ERK 1, these inhibitors can modulate intracellular signaling pathways, which are often dysregulated in various diseases. Understanding the role of ERK 1 in various cellular processes has become an essential area of investigation in the scientific community, and ERK 1 inhibitors have become valuable tools in these endeavors. It is important to note that while ERK 1 inhibitors show promise in experimental settings, further research is required to assess their safety, efficacy, and applications. The ongoing studies aim to shed light on the specific contexts in which ERK 1 inhibitors could be utilized, which may have implications for various fields of research. Nonetheless, the chemical class of ERK 1 inhibitors represents a significant advancement in understanding cellular signaling pathways and provides a foundation for future developments.

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Items 1 to 10 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ERK Inhibitor II, FR180204

865362-74-9sc-203945
sc-203945A
sc-203945B
sc-203945C
1 mg
5 mg
10 mg
50 mg
$108.00
$162.00
$234.00
$924.00
45
(2)

ERK Inhibitor II, FR180204 (CAS 865362-74-9) is a chemical compound known for its inhibitory action on ERK 1, a member of the extracellular signal-regulated kinase family. By selectively targeting ERK 1, it modulates specific cellular signaling pathways, contributing to potential insights into cellular processes.

SC1 (Pluripotin)

839707-37-8sc-255607
sc-255607A
sc-255607B
sc-255607C
1 mg
5 mg
10 mg
25 mg
$164.00
$195.00
$464.00
$764.00
(1)

SC1 (Pluripotin), with CAS number 839707-37-8, is a chemical compound known for its inhibitory action on ERK 1, a critical protein involved in cellular signaling pathways. Through its specific inhibitory effect on ERK 1, SC1 modulates cellular responses and shows potential relevance in various biological research contexts.

Ulixertinib

869886-67-9sc-507296
10 mg
$176.00
(0)

Ulixertinib is an available, highly selective ERK1/2 inhibitor which has shown promise in research studies and biotechnology research.

Olomoucine

101622-51-9sc-3509
sc-3509A
5 mg
25 mg
$72.00
$274.00
12
(1)

Olomoucine (CAS 101622-51-9) is a chemical compound known for its inhibitory action on the enzyme ERK 1. It effectively hinders the activity of ERK 1, which plays a crucial role in cell signaling pathways. This inhibition can have various biological implications without mentioning specific therapeutic uses.

Evodiamine

518-17-2sc-201479
sc-201479A
20 mg
100 mg
$20.00
$71.00
2
(1)

Evodiamine (CAS 518-17-2) is a chemical compound known for its inhibitory action on ERK 1, a key protein involved in cell signaling pathways. Through its inhibitory effect, Evodiamine interferes with ERK 1's activity, which may have implications in cellular processes and functions.

GDC0994

1453848-26-4sc-507297
10 mg
$130.00
(0)

GDC-0994 is a potent and selective ERK1/2 inhibitor which has demonstrated antitumor effects in research studies for advanced solid tumors.

p38 MAP Kinase Inhibitor IV

1638-41-1sc-204159
5 mg
$260.00
(0)

P38 MAP Kinase Inhibitor IV (CAS 1638-41-1) is a chemical compound known for its inhibitory action on ERK 1, a protein involved in cellular signaling pathways. By blocking ERK 1 activity, it modulates specific cellular processes without implying any medical or therapeutic implications.

SCH772984

942183-80-4sc-473205
5 mg
$363.00
5
(0)

SCH772984 (CAS 942183-80-4) is a chemical compound known for its inhibitory action on ERK 1, a crucial protein kinase involved in cell signaling pathways. By targeting ERK 1, SCH772984 modulates cellular processes associated with this kinase, potentially impacting various cellular responses.

LY3214996

1951483-29-6sc-507299
5 mg
$260.00
(0)

LY3214996 is a selective ERK1/2 inhibitor which has shown activity against cancer cells in research studies and is under evaluation in research models for various malignancies.

VX-11e

896720-20-0sc-507301
10 mg
$180.00
(0)

VTX-11e is a potent and selective inhibitor of ERK1/2, which has shown efficacy against various cancer cell lines and is being evaluated for its therapeutic potential.