EPX Inhibitors
The class of chemicals identified as EPX inhibitors comprises a diverse range of compounds that can indirectly influence the activity of eosinophil peroxidase. These inhibitors do not directly bind to or deactivate EPX. Instead, they operate by modulating various biochemical pathways and cellular processes that indirectly impact the enzyme's function. For instance, some of these chemicals, such as Ascorbic Acid and Quercetin, function as antioxidants. They mitigate the oxidative products generated by EPX, thereby reducing its effective action within the cellular environment.
Other compounds in this class, such as Diphenyleneiodonium Chloride and Apocynin, target different enzymes or cellular components that are upstream or parallel to the pathways involving EPX. By inhibiting these enzymes, like NADPH oxidase, they consequently alter the cellular redox state, indirectly affecting EPX activity. Additionally, compounds like Indomethacin and Ketoprofen, which influence inflammatory pathways, also play a role in modulating EPX activity.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Reduces EPX activity by competing for its substrates and altering its redox state. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $43.00 $155.00 $393.00 $862.00 $90.00 | 8 | |
Inhibits heme-containing enzymes like EPX by binding to the heme group. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Acts as an antioxidant, reducing the oxidative products generated by EPX. | ||||||
1-Iodo-4-nitrobenzene | 636-98-6 | sc-229793A sc-229793 sc-229793B sc-229793C sc-229793D | 5 g 25 g 100 g 500 g 1 kg | $16.00 $48.00 $152.00 $416.00 $769.00 | ||
Inhibits flavoenzymes, which can indirectly reduce EPX activity by altering cellular redox states. | ||||||
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
Inhibits NADPH oxidase, indirectly reducing the production of reactive oxygen species which EPX uses. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates various signaling pathways, indirectly affecting EPX activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Acts as an antioxidant and modulates signaling pathways that can influence EPX activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Interferes with inflammatory pathways, potentially reducing the activation of EPX. | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $131.00 | ||
Inhibits xanthine oxidase, indirectly affecting reactive oxygen species production and EPX activity. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $29.00 $38.00 | 18 | |
Inhibits cyclooxygenase, affecting inflammatory pathways that can modulate EPX activity. | ||||||