ENDOGL1 inhibitors function primarily by mitigating oxidative stress or suppressing the immune response. For instance, N-acetyl-cysteine is an antioxidant that can reduce oxidative stress. Given that ENDOGL1 is sensitive to oxidative stress, the reduction of this stress by N-acetyl-cysteine can indirectly inhibit the functional activity of ENDOGL1. Similarly, ethanol and sodium nitroprusside can increase oxidative stress, which can indirectly lead to the inhibition of ENDOGL1's functional activity.
On the other hand, certain ENDOGL1 inhibitors, such as dexamethasone and prednisone, are glucocorticoids that can suppress the immune response. Since ENDOGL1 is involved in inflammatory responses, the suppression of the immune response by these glucocorticoids can lead to the indirect inhibition of ENDOGL1's functional activity. Non-steroidal anti-inflammatory drugs like aspirin, ibuprofen, and naproxen inhibit cyclooxygenases, which canalso lead to the indirect inhibition of ENDOGL1's functional activity. Immunosuppressive drugs such as hydroxychloroquine, methotrexate, cyclosporine, and tacrolimus can reduce the immune response or disrupt T cell signaling, which can indirectly inhibit the functional activity of ENDOGL1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
N-acetyl-cysteine is an antioxidant that can reduce oxidative stress. ENDOGL1 is sensitive to oxidative stress, and by decreasing this stress, N-acetyl-cysteine can indirectly inhibit the functional activity of ENDOGL1. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Sodium nitroprusside generates nitric oxide and can increase oxidative stress. The increase in oxidative stress can lead to the inhibition of ENDOGL1's functional activity. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that can suppress the immune response. Since ENDOGL1 is involved in inflammatory responses, the suppression of the immune response by Dexamethasone can indirectly inhibit the functional activity of ENDOGL1. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
Aspirin is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenases. Given that ENDOGL1 is involved in inflammatory responses, the inhibition of cyclooxygenases by aspirin can lead to the indirect inhibition of ENDOGL1's functional activity. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $53.00 $88.00 | 6 | |
Ibuprofen is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenases. Given that ENDOGL1 is involved in inflammatory responses, the inhibition of cyclooxygenases by ibuprofen can lead to the indirect inhibition of ENDOGL1's functional activity. | ||||||
Naproxen | 22204-53-1 | sc-200506 sc-200506A | 1 g 5 g | $24.00 $41.00 | ||
Naproxen is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenases. Given that ENDOGL1 is involved in inflammatory responses, the inhibition of cyclooxygenases by naproxen can lead to the indirect inhibition of ENDOGL1's functional activity. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $42.00 $136.00 $676.00 | 2 | |
Prednisone is a glucocorticoid that can suppress the immune response. Since ENDOGL1 is involved in inflammatory responses, the suppression of the immune response by prednisone can indirectly inhibit the functional activity of ENDOGL1. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $57.00 | 1 | |
Hydroxychloroquine is an immunosuppressive drug that can reduce the immune response. Since ENDOGL1 is involved in inflammatory responses, the reduction of the immune response by hydroxychloroquine can indirectly inhibit the functional activity of ENDOGL1. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate is an immunosuppressive drug that can reduce the immune response. Given that ENDOGL1 is involved in inflammatory responses, the reduction of the immune response by methotrexate can indirectly inhibit the functional activity of ENDOGL1. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporine is an immunosuppressive drug that can inhibit calcineurin, disrupting T cell signaling. As ENDOGL1 is involved in inflammatory responses, the disruption of T cell signaling by cyclosporine can indirectly inhibit the functional activity of ENDOGL1. | ||||||