Molecular structure of Prednisone, CAS Number: 53-03-2
Prednisone (CAS 53-03-2)
See product citations (2)
Alternate Names:
1-Dehydrocortisone; 1-Cortisone
Application:
Prednisone is downregulates TNF-α production and NF-κB expression
CAS Number:
53-03-2
Molecular Weight:
358.43
Molecular Formula:
C21H26O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Prednisone is a corticosteroid may have anti-inflammatory and immunosuppressant properties. Prednisone functions by binding to intracellular glucocorticoid receptors, leading to the upregulation of anti-inflammatory genes and the downregulation of pro-inflammatory genes. This results in the suppression of the immune response and the reduction of inflammation.
Prednisone (CAS 53-03-2) References
- Prednisone per os is likely to have limited efficacy in horses. | Peroni, DL., et al. 2002. Equine Vet J. 34: 283-7. PMID: 12108748
- Prednisone treatment in cirrhosis of the liver. | WINKLER, K. and TYGSTRUP, N. 1957. Acta Med Scand. 157: 149-56. PMID: 13410552
- Prednisone therapy for patients with asthma. | Blake, GJ. 1990. Nursing. 20: 120. PMID: 2267065
- Efficacy and safety of modified-release prednisone in patients with rheumatoid arthritis. | Krasselt, M. and Baerwald, C. 2016. Drug Des Devel Ther. 10: 1047-58. PMID: 27022244
- [A vulnerable elderly man with prednisone-induced delirium]. | Otten, RI., et al. 2019. Ned Tijdschr Geneeskd. 163: PMID: 31120224
- Patterns of Prednisone Use in Patients with Rheumatoid Arthritis Initiating Treatment with Tocilizumab in Routine US Clinical Practice. | Pappas, DA., et al. 2019. Rheumatol Ther. 6: 421-433. PMID: 31240499
- The pharmaceutical prednisone affects sheepshead minnow (Cyprinodon variegatus) metabolism and swimming performance. | Thibault, O., et al. 2021. Comp Biochem Physiol A Mol Integr Physiol. 253: 110851. PMID: 33238196
- Outcomes of prednisone-tapering regimens for cardiac sarcoidosis: A retrospective analysis demonstrating a benefit of infliximab. | Judson, MA., et al. 2022. Respir Med. 203: 107004. PMID: 36240614
- Distribution and metabolism of prednisone in mice, dogs, and monkeys. | El Dareer, SM., et al. 1977. Cancer Treat Rep. 61: 1279-89. PMID: 412589
- Effects of prednisone on thyroid and gonadal endocrine function in dogs. | Kemppainen, RJ., et al. 1983. J Endocrinol. 96: 293-302. PMID: 6827210
- Oral prednisone for chronic active liver disease: dose responses and bioavailability studies. | Uribe, M., et al. 1978. Gut. 19: 1131-5. PMID: 744499
- Prednisone dose limitation of growth hormone treatment of steroid-induced growth failure. | Rivkees, SA., et al. 1994. J Pediatr. 125: 322-5. PMID: 8040785
- Prednisone for chronic active liver disease: pharmacokinetics, including conversion to prednisolone. | Schalm, SW., et al. 1977. Gastroenterology. 72: 910-3. PMID: 849821
Inhibitor of:
apoA-V, apoH, BTN3A2, BTN3A3, C20orf54, C4 A, CADM1 (Cell Adhesion Molecule 1), CD1C, CD79A, CRISP-8, CysLT1 Receptor, DLEU7, Dystrophin-Glycoprotein Complex (DGC; Sarcospan), ENDOGL1, ESM-1, F5 TCR α, F5 TCR β, Gm14139, Gm14306, ICSBP, IFRD2, IgA, IgAight chain, Igbp1b, IgG, IgG2, IgG2a, IL-11Rα, IL-13Rα2, IL-17E, IL-2Rα, ITI-H3, KIR2DL1, KIR3DL3, KNAT1, Lingo-4, LOC643327, LTB4DH, OG1, Olfr427, Olfr825, ORG, osteocalcin, OTTMUSG00000017373, OX2, PAF acetylhydrolase 2, PMP22, PTG, R-Spondin2, Sectm1a, SLAMF6, Tenascin-X, TNFα-IP 8, Trav12-1, Trav6d-5, Trefoil factor (TFF), and YKL-39.Activator of:
γ2-Syntrophin, AGP-1, AKR7A4, Bu-1a, C1INH, CD137L, CD53, CYP3A43, DOCK 2, Fc ε RIγ, fetuin-A, FRG1B, IFN-γRβ, Ig κ chain, Ig λ chain, IL-11, Intelectin-2, katacalcin, KIAA0649, MACHβ1, Med18, OLFML3, PIBF, PSG, RhCE, SerpinB6, SH2D1A, and Slfn1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Prednisone, 1 g | sc-205816 | 1 g | $41.00 | |||
Prednisone, 5 g | sc-205816A | 5 g | $133.00 | |||
Prednisone, 25 g | sc-205816B | 25 g | $663.00 |