ENDOGL1 Activators
ENDOGL1 activators are diverse in their chemical nature and underlying mechanisms of action. These activators work through various biochemical and cellular pathways, all of which ENDOGL1 is directly involved in. Forskolin and Clozapine, for instance, enhance the functional activity of ENDOGL1 through the cAMP and GPCR signaling pathways, respectively. Dexamethasone, on the other hand, works by elevating the PI3K/AKT pathway, thereby enhancing the function of ENDOGL1.
On the other hand, Acetylcholine and Epinephrine activate the GPCR signaling pathway, enhancing the function of ENDOGL1. BDNF, VEGF, EGF, Nerve growth factor (NGF), Platelet-derived growth factor (PDGF), and Insulin are growth factors that activate specific receptors, leading to the stimulation of the PI3K/Akt and Ras/ERK pathways. As ENDOGL1 is involved in these pathways, these growth factorscan enhance the function of ENDOGL1. Lastly, Rapamycin, an mTOR inhibitor, influences the PI3K/AKT/mTOR pathway to enhance ENDOGL1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a direct activator of adenylyl cyclase, leading to increased cAMP levels. ENDOGL1 is known to be involved in the cAMP signaling pathway, and the increase in cAMP can lead to functional activation of ENDOGL1. | ||||||
Clozapine | 5786-21-0 | sc-200402 sc-200402A sc-200402B sc-200402C | 50 mg 500 mg 5 g 10 g | $69.00 $364.00 $2500.00 $4100.00 | 11 | |
Clozapine is an atypical antipsychotic that can activate G-protein-coupled receptors (GPCRs). ENDOGL1 is involved in GPCR signaling, so the activation of these receptors by Clozapine can enhance the function of ENDOGL1. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine is a hormone and neurotransmitter that activates adrenergic receptors, which are GPCRs. As ENDOGL1 is involved in GPCR signaling, the activation of these receptors can enhance the function of ENDOGL1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, can influence the PI3K/AKT/mTOR pathway, which ENDOGL1 is known to regulate. This can enhance the functional activity of ENDOGL1. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the insulin receptor, leading to activation of the PI3K/Akt pathway. As ENDOGL1 is involved in this pathway, insulin can enhance the function of ENDOGL1. | ||||||