EMSY Activators
EMSY activators are a class of compounds that target EMSY, a protein that has been implicated in chromatin remodeling and transcriptional regulation. EMSY is believed to play a role in the regulation of gene expression by interacting with various components of the transcription machinery and modifying the structure of chromatin, thereby influencing the accessibility of genes to be transcribed.
Direct activators of EMSY may interact with the protein to enhance its ability to bind to chromatin or to other transcriptional co-regulators. This could involve stabilizing the conformation of EMSY that has a higher affinity for its binding partners or promoting post-translational modifications that enhance EMSY activity. For instance, they may encourage acetylation or phosphorylation that could foster EMSY's interaction with the transcription machinery, promoting gene expression regulation. Alternatively, indirect EMSY activators might work by increasing the expression level of EMSY, either through upregulation of its transcription or by stabilizing its mRNA, leading to a higher concentration of the EMSY protein within the cell. They could also affect various signaling pathways that indirectly increase EMSY's activity or availability, such as inhibiting negative regulators of EMSY or modulating the activity of proteins that interact with EMSY.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Estradiol, an estrogen hormone, can activate the PI3K/AKT pathway, upregulating the function of EMSY, which is a co-activator of PI3K/AKT signaling. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the PI3K/AKT pathway. EMSY is a co-activator of this pathway, and its function is enhanced when this pathway is activated. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $104.00 $141.00 | 14 | |
Triciribine is an AKT inhibitor. When AKT is inhibited, the PI3K pathway, which EMSY is a co-activator of, is less suppressed, leading to enhanced EMSY function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, which can lead to activation of the PI3K/AKT pathway, enhancing the function of EMSY, a co-activator of the pathway. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates SIRT1, which can indirectly enhance EMSY function via the PI3K/AKT pathway, of which EMSY is a co-activator. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Niacin is a precursor of NAD+, which is a co-factor for SIRT1. Increased SIRT1 activity can enhance EMSY function via the PI3K/AKT pathway, of which EMSY is a co-activator. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin activates SIRT1, which can indirectly enhance EMSY function via the PI3K/AKT pathway, of which EMSY is a co-activator. | ||||||