Date published: 2026-2-14

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ELFN1 Inhibitors

ELFN1 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the ELFN1 protein, also known as Extracellular Leucine-Rich Repeat and Fibronectin Type III Domain Containing 1. ELFN1 is a membrane-associated protein expressed in the brain, particularly in regions involved in synaptic transmission and neuronal circuitry. While its precise function is still an area of active research, ELFN1 is believed to play a role in the regulation of synaptic connectivity and neuronal signaling. Inhibitors of ELFN1 are developed to interfere with its function or activity, potentially influencing synapse formation, synaptic plasticity, and other processes related to neural communication.

The mechanisms by which ELFN1 inhibitors function can vary based on their chemical structures and binding properties. Some inhibitors may directly interact with ELFN1, preventing its association with other synaptic proteins or affecting its membrane localization. Others may modulate the stability or conformation of ELFN1, disrupting its role in synaptic adhesion or signaling. By inhibiting ELFN1, these compounds have the potential to impact synaptic function, neuronal connectivity, and neural circuitry, which may have implications for our understanding of brain development and function. Ongoing research in this field aims to elucidate the precise mechanisms and downstream effects of ELFN1 inhibition, contributing to our knowledge of its role in neural biology and synaptic regulation.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

A compound that inhibits bacterial RNA polymerase, potentially reducing transcription levels in prokaryotic cells, and may influence eukaryotic transcription factors.

Allicin

539-86-6sc-202449
sc-202449A
1 mg
5 mg
$489.00
$1557.00
7
(1)

A compound from garlic, known to exhibit a variety of biological effects that could include modulation of transcription factor activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

A biologically active compound of turmeric, which can modulate various signal transduction pathways and potentially affect gene expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenol that acts on multiple cellular targets, potentially influencing gene transcription and expression patterns.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A metabolite of vitamin A that acts as a ligand for retinoic acid receptors and can regulate gene expression by influencing transcription.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

A flavonoid with antioxidant properties, known to affect signaling pathways and possibly gene transcription.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

A compound that possesses histone deacetylase inhibitory activity, potentially affecting chromatin structure and gene expression.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

An inhibitor of heat shock protein 90 (HSP90) which could destabilize client proteins, potentially affecting protein levels and expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

An isoflavone that acts as a tyrosine kinase inhibitor and might modulate signal transduction pathways influencing gene expression.

Sulfasalazine

599-79-1sc-204312
sc-204312A
sc-204312B
sc-204312C
1 g
2.5 g
5 g
10 g
$61.00
$77.00
$128.00
$209.00
8
(1)

A drug that contains salicylate and has been shown to inhibit the NF-kB pathway, which could potentially affect gene regulation.