ELFN1 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the ELFN1 protein, also known as Extracellular Leucine-Rich Repeat and Fibronectin Type III Domain Containing 1. ELFN1 is a membrane-associated protein expressed in the brain, particularly in regions involved in synaptic transmission and neuronal circuitry. While its precise function is still an area of active research, ELFN1 is believed to play a role in the regulation of synaptic connectivity and neuronal signaling. Inhibitors of ELFN1 are developed to interfere with its function or activity, potentially influencing synapse formation, synaptic plasticity, and other processes related to neural communication.
The mechanisms by which ELFN1 inhibitors function can vary based on their chemical structures and binding properties. Some inhibitors may directly interact with ELFN1, preventing its association with other synaptic proteins or affecting its membrane localization. Others may modulate the stability or conformation of ELFN1, disrupting its role in synaptic adhesion or signaling. By inhibiting ELFN1, these compounds have the potential to impact synaptic function, neuronal connectivity, and neural circuitry, which may have implications for our understanding of brain development and function. Ongoing research in this field aims to elucidate the precise mechanisms and downstream effects of ELFN1 inhibition, contributing to our knowledge of its role in neural biology and synaptic regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
A compound that inhibits bacterial RNA polymerase, potentially reducing transcription levels in prokaryotic cells, and may influence eukaryotic transcription factors. | ||||||
Allicin | 539-86-6 | sc-202449 sc-202449A | 1 mg 5 mg | $489.00 $1557.00 | 7 | |
A compound from garlic, known to exhibit a variety of biological effects that could include modulation of transcription factor activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A biologically active compound of turmeric, which can modulate various signal transduction pathways and potentially affect gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol that acts on multiple cellular targets, potentially influencing gene transcription and expression patterns. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A that acts as a ligand for retinoic acid receptors and can regulate gene expression by influencing transcription. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with antioxidant properties, known to affect signaling pathways and possibly gene transcription. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A compound that possesses histone deacetylase inhibitory activity, potentially affecting chromatin structure and gene expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
An inhibitor of heat shock protein 90 (HSP90) which could destabilize client proteins, potentially affecting protein levels and expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor and might modulate signal transduction pathways influencing gene expression. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $61.00 $77.00 $128.00 $209.00 | 8 | |
A drug that contains salicylate and has been shown to inhibit the NF-kB pathway, which could potentially affect gene regulation. | ||||||