Elf-1 Activators
Inhibitors of ELF1, as discussed above, predominantly act indirectly. ELF1, being a transcription factor, is involved in regulating the expression of a wide range of genes, especially those related to immune responses and the development of blood cells. The chemicals listed here do not target ELF1 directly but instead influence various signaling pathways or cellular processes that can indirectly affect ELF1 activity or its expression.
Compounds like JQ1 and I-BET762 target the BET family of bromodomain proteins, which play a crucial role in regulating gene expression by modulating chromatin structure. By influencing these regulatory mechanisms, these compounds can indirectly affect the transcriptional activity of ELF1. Histone deacetylase inhibitors like Trichostatin A and DNA methyltransferase inhibitors like 5-Azacytidine also alter gene expression patterns, which could impact ELF1's regulatory functions. Inhibitors of key signaling pathways, such as Rapamycin (mTOR inhibitor), LY294002 (PI3K inhibitor), PD98059 (MEK inhibitor), and SP600125 (JNK inhibitor), can indirectly influence ELF1 by altering the cellular environment and signaling cascades that ELF1 is involved in.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 targets the BET family of bromodomain proteins, potentially affecting ELF1 expression by altering chromatin accessibility and gene transcription. | ||||||
GSK 525762A | 1260907-17-2 | sc-490339 sc-490339A sc-490339B sc-490339C sc-490339D | 5 mg 10 mg 50 mg 100 mg 1 g | $300.00 $540.00 $940.00 $1680.00 $5900.00 | ||
I-BET762, another BET bromodomain inhibitor, may indirectly modulate ELF1 activity by influencing transcriptional regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, could indirectly affect ELF1 by altering cellular growth and survival pathways, which ELF1 is involved in. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, with its anti-inflammatory and anticancer properties, might modulate ELF1-related pathways or expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, can affect gene expression patterns, potentially impacting ELF1 activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, may influence ELF1 expression by altering epigenetic marks on DNA. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, could indirectly affect ELF1 activity by modulating stress-related signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, a PI3K inhibitor, might influence ELF1 by altering signaling pathways involved in cell proliferation and survival. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, an MEK inhibitor, can affect MAPK/ERK pathway, potentially influencing ELF1 activity. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib, a proteasome inhibitor, could indirectly impact ELF1 through its effects on protein degradation pathways. | ||||||