ECOP Activadores
ZNF425, as a zinc finger protein, is intricately involved in the regulation of gene expression through its DNA-binding capability. The chemicals listed are not direct activators of ZNF425 but rather influence its activity or expression indirectly by targeting key cellular processes like DNA methylation, histone modification, and zinc homeostasis. Compounds such as 5-Azacytidine and RG108, which inhibit DNA methyltransferases, can alter the epigenetic landscape, potentially affecting the transcriptional regulation activities of ZNF425. Histone deacetylase (HDAC) inhibitors like Trichostatin A and SAHA modify chromatin structure, which can have downstream effects on ZNF425-mediated gene expression.
Additionally, the function of zinc finger proteins like ZNF425 is closely tied to zinc availability, and compounds that modulate zinc levels, such as Disulfiram and Pyrithione Zinc, may indirectly impact ZNF425 activity. Furthermore, inhibitors of histone acetyltransferases (e.g., C646) and histone methyltransferases (e.g., BIX-01294) can also affect the expression and function of genes regulated by ZNF425. Mithramycin A, with its DNA-binding ability, could compete with ZNF425 for DNA binding sites, influencing its regulatory roles.
JQ1 and DZNep target other aspects of chromatin accessibility and gene expression, further illustrating the complex interplay between various epigenetic modifiers and zinc finger proteins like ZNF425. Genistein's broad impact on signal transduction pathways can also have indirect effects on the transcriptional regulatory functions of ZNF425.
These chemical compounds provide valuable tools for studying the biological functions and regulatory mechanisms associated with ZNF425. By influencing the epigenetic and transcriptional landscape in which ZNF425 operates, they offer insights into the broader context of gene regulation and the intricate network of interactions that govern cellular processes. Such understanding is crucial for unraveling the complex roles of zinc finger proteins in gene expression and cellular function.
| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Un inhibidor de la metiltransferasa del ADN, la 5-azacitidina, puede influir indirectamente en el ZNF425 alterando los patrones de metilación del ADN y afectando así a la expresión génica. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
La tricostatina A, un inhibidor de HDAC, puede afectar a la expresión de ZNF425 alterando la estructura de la cromatina y la transcripción génica. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
RG108, un inhibidor de la metiltransferasa del ADN, puede modular indirectamente la expresión de ZNF425 a través de cambios en la metilación del ADN. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Le disulfirame peut chélater les ions de zinc, ce qui peut influencer la fonction des protéines à doigt de zinc comme ZNF425. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Como fuente de zinc, el piritionato de zinc podría afectar indirectamente a la funcionalidad de ZNF425 modulando la disponibilidad de zinc. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
El C646, un inhibidor de la histona acetiltransferasa p300/CBP, puede afectar indirectamente al ZNF425 alterando la acetilación de histonas y la expresión génica. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Un antibiotique se liant à l'ADN, la mithramycine A, pourrait influencer ZNF425 en entrant en compétition avec lui pour les sites de liaison à l'ADN. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $36.00 $110.00 $400.00 | ||
El BIX-01294, un inhibidor de la histona metiltransferasa G9a, podría afectar a la expresión de ZNF425 alterando la metilación de histonas y la estructura de la cromatina. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
El JQ1, un inhibidor del bromodominio BET, puede influir potencialmente en la actividad del ZNF425 modulando la accesibilidad del factor de transcripción a la cromatina. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
La genisteína, un inhibidor de la tirosina cinasa, podría influir indirectamente en la actividad de ZNF425 a través de vías implicadas en la transducción de señales y la regulación transcripcional. | ||||||