E2F-6 Activators
The chemical class of E2F-6 Activators includes compounds that can indirectly influence E2F-6 function through their effects on gene expression regulation, chromatin remodeling, and cellular signaling pathways. E2F-6, being involved in transcriptional repression and cell cycle control, is responsive to changes in the cellular environment and gene expression regulation.
Compounds like Retinoic Acid and HDAC inhibitors (Trichostatin A, Vorinostat, Sodium Butyrate) can modulate gene expression patterns and chromatin structure, potentially affecting E2F-6 function. These compounds are known to influence the regulation of genes involved in cell cycle and differentiation processes, thereby potentially impacting E2F-6 activity. Inhibitors of signaling pathways, such as PD98059 (a MEK inhibitor) and Lithium Chloride (a GSK-3 inhibitor), as well as natural compounds like Resveratrol, Curcumin, Genistein, and EGCG, could indirectly influence E2F-6 activity. These compounds modulate various signaling cascades and cellular responses, which can impact the function of transcription factors like E2F-6.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Influences gene expression, potentially impacting E2F6 activity in cell cycle regulation and differentiation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
An HDAC inhibitor, affects chromatin structure and gene expression, potentially influencing E2F6. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially affecting E2F6 function by altering gene expression patterns. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another HDAC inhibitor, might affect E2F6 by altering chromatin remodeling and gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Modulates sirtuin pathways, potentially influencing E2F6 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MEK inhibitor, could indirectly affect E2F6 activity by altering MAPK pathway signaling. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Influences various signaling pathways, potentially affecting E2F6 activity indirectly. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As an HDAC inhibitor, can impact gene expression, potentially modulating E2F6 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which may indirectly influence E2F6 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor; suggested to influence signaling pathways, potentially affecting E2F6. | ||||||