The class of chemical compounds referred to as Dmrtc1c Activators is a specialized group with a remarkable capacity to instigate the expression of the Dmrtc1c gene. Dmrtc1c, a well-characterized protein, plays a pivotal role in various biological processes, particularly in the regulation of gene expression. These activators, marked by their diverse chemical structures and intricate mechanisms of action, serve as essential tools for scientists and researchers deeply engaged in the exploration of gene expression and the underlying cellular regulatory systems. One of the most intriguing aspects of Dmrtc1c activators is their ability to modulate the transcriptional machinery responsible for governing the Dmrtc1c gene. These compounds are adept at influencing multiple phases of gene transcription, including initiation and elongation, by interacting with specific regulatory elements. They often target the promoter regions or enhancers, effectively enhancing the gene's transcriptional activity. Furthermore, certain members of this chemical class are known to exert their effects through epigenetic modifications.
This includes the modulation of histone acetylation and DNA demethylation, which collectively create a permissive environment for increased accessibility of the Dmrtc1c gene, promoting its expression. In addition to these mechanisms, some Dmrtc1c activators influence critical intracellular signaling pathways, such as the MAPK/ERK and PI3K/AKT cascades. These pathways ultimately converge on transcriptional regulators that control Dmrtc1c expression, leading to heightened gene transcription. Overall, Dmrtc1c activators are invaluable tools in the scientific arsenal, facilitating the investigation of intricate gene expression regulation networks. Their utility extends to uncovering fundamental insights into cellular processes making them a cornerstone in molecular and cellular biology research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that stimulates dmrtc1c expression through transcriptional activation by binding to glucocorticoid receptors, which then act as transcription factors for dmrtc1c. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic Acid functions as a histone deacetylase inhibitor, promoting dmrtc1c expression by increasing histone acetylation, thus making the gene more accessible for transcription. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates dmrtc1c expression by modulating specific signaling pathways, such as the MAPK/ERK and PI3K/AKT pathways, which ultimately lead to increased transcription of dmrtc1c. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine upregulates dmrtc1c by stabilizing its mRNA, preventing degradation, and allowing for a more extended period of gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin activates dmrtc1c transcription by binding to its promoter region, enhancing RNA polymerase binding and promoting gene expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG-132 increases dmrtc1c levels by inhibiting the proteasome, preventing dmrtc1c protein degradation, and leading to higher expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid acts as a ligand for nuclear receptors, stimulating dmrtc1c expression through the activation of specific receptors and downstream signaling. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is an HDAC inhibitor, promoting dmrtc1c expression by increasing histone acetylation and enhancing gene accessibility. | ||||||
Proteasome Inhibitor I | 158442-41-2 | sc-3127 | 1 mg | $86.00 | 1 | |
Proteasome Inhibitor I triggers dmrtc1c upregulation by inhibiting the proteasomal degradation of dmrtc1c protein, leading to increased protein levels. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin enhances dmrtc1c expression by disrupting translational repression mechanisms, allowing for increased protein synthesis. | ||||||