DDX16 Activators
DDX16 activators belong to a class of chemicals that specifically target the DDX16 protein, a member of the DEAD-box RNA helicase family. DDX16 plays a crucial role in RNA metabolism by participating in various processes, including RNA splicing, export, and translation. The activators are designed to enhance the activity of DDX16, potentially by increasing its RNA-binding affinity or promoting its ATPase activity. By doing so, these chemicals can modulate the function of DDX16 and, consequently, influence the overall RNA metabolism within the cell.
The development of DDX16 activators is of interest due to the essential role of DDX16 in various cellular processes. Modulating the activity of DDX16 could have implications for understanding RNA metabolism and its regulation. Additionally, since DDX16 dysregulation has been implicated in certain diseases, such as cancer and viral infections, these activators could serve as valuable tools for studying the role of DDX16 in disease pathology. Overall, DDX16 activators represent a promising class of compounds that could provide valuable insights into RNA metabolism and its associated cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Augments cellular ATP levels which can directly enhance DDX16's ATP-dependent RNA unwinding activity. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Raises cellular cAMP levels which can stimulate RNA metabolism pathways, necessitating increased DDX16 activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Stimulates AMPK pathway which indirectly boosts RNA processing activities requiring enhanced DDX16 action. | ||||||
D-(−)-Ribose | 50-69-1 | sc-221458 sc-221458A sc-221458B sc-221458C sc-221458D sc-221458E sc-221458F | 5 g 25 g 100 g 250 g 1 kg 5 kg 10 kg | $25.00 $57.00 $110.00 $230.00 $600.00 $1200.00 $2000.00 | 1 | |
Enhances RNA synthesis; this increases demand for DDX16's role in RNA unwinding and processing. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates cAMP levels which can indirectly augment RNA processing pathways involving DDX16. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Activates the Nrf2 pathway, which has roles in modulating gene transcription, indirectly increasing the need for DDX16. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Suppresses NF-κB activation; altering gene expression patterns to indirectly require more DDX16 activity. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $25.00 $75.00 $150.00 | 32 | |
Modifies multiple signaling pathways, indirectly increasing DDX16 demand in RNA processing functions. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Changes gene expression patterns to indirectly raise the requirement for DDX16 in RNA unwinding tasks. | ||||||
Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $27.00 | 6 | |
Engages the Nrf2 pathway which modifies gene transcription, potentially enhancing the need for active DDX16. | ||||||