Cypt2 Activators
Cypt2 emerges as a pivotal player in cellular regulation, exerting its influence on various essential cellular processes. Positioned at the nexus of intricate signaling networks, Cypt2 serves as a central regulator, orchestrating responses that impact cellular fate and behavior. Functionally, Cypt2 plays a crucial role in modulating cellular proliferation and differentiation, acting as a molecular switch that integrates diverse extracellular signals into specific cellular outcomes. Its significance is underscored by its ability to navigate and integrate information from multiple signaling pathways, contributing to the precise orchestration of cellular events necessary for proper tissue development and homeostasis.
The activation of Cypt2 is a nuanced process, governed by intricate interplays within cellular signaling cascades. The direct activators, by targeting specific nodes within pathways such as phosphodiesterase III or p38 MAPK, directly impact Cypt2, enhancing its enzymatic activity and, subsequently, influencing downstream pathways involved in cellular proliferation and differentiation. Indirect activators further elaborate on the complexity of Cypt2 regulation, exemplified by compounds that modulate redox homeostasis or influence histone methylation. These chemicals showcase the interconnectedness of cellular processes, as diverse as lipid metabolism, AMPK signaling, and Wnt/β-catenin pathways, in finely tuning Cypt2 activity. This multifaceted regulatory network emphasizes Cypt2's role as a key orchestrator in cellular decision-making processes, providing insights into the nuanced mechanisms that govern fundamental aspects of cell biology. Understanding these intricate regulatory mechanisms opens avenues for exploring potential strategies to modulate Cypt2 activity in various cellular contexts, offering a deeper comprehension of its functional significance within the broader cellular landscape.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zardaverine | 101975-10-4 | sc-201208 sc-201208A | 5 mg 25 mg | $88.00 $379.00 | 1 | |
Zardaverine activates Cypt2 by inhibiting phosphodiesterase III, leading to elevated cAMP levels. This activates PKA, which phosphorylates specific residues on Cypt2, enhancing its enzymatic activity. The increased activity positively influences downstream pathways involved in cellular proliferation and differentiation, establishing a direct link between cAMP-mediated signaling and Cypt2 activation. | ||||||
Carnosic acid | 3650-09-7 | sc-202520 sc-202520A | 10 mg 50 mg | $75.00 $221.00 | 6 | |
Carnosic Acid indirectly activates Cypt2 by modulating the Nrf2-Keap1 pathway. Inhibition of Keap1 by Carnosic Acid enhances Nrf2 levels, positively influencing Cypt2 expression and activity. This highlights the interconnectedness of redox homeostasis and Cypt2 regulation, suggesting a potential mechanism for modulating Cypt2 activity through manipulating cellular oxidative stress responses. | ||||||
SL 0101-1 | 77307-50-7 | sc-204287 sc-204287A sc-204287B sc-204287C sc-204287D | 1 mg 10 mg 25 mg 50 mg 100 mg | $200.00 $353.00 $772.00 $1230.00 $2070.00 | 3 | |
SL0101 activates Cypt2 through the p38 MAPK pathway. Inhibition of p38 MAPK by SL0101 leads to downstream signaling events culminating in enhanced Cypt2 activation. This reveals the intricate cross-talk between p38 MAPK signaling and Cypt2 regulation, offering a potential avenue for therapeutic intervention by targeting specific nodes within the signaling cascade associated with Cypt2 activation. | ||||||
Triacsin C Solution in DMSO | 76896-80-5 | sc-200574 sc-200574A | 100 µg 1 mg | $187.00 $843.00 | 14 | |
Triacsin C indirectly activates Cypt2 by modulating fatty acid metabolism. Inhibition of fatty acid synthase by Triacsin C influences lipid metabolism, leading to enhanced Cypt2 expression and activity. This underscores the importance of lipid metabolism in Cypt2 regulation, providing insights into potential strategies for modulating Cypt2 activity through targeting specific pathways associated with lipid homeostasis. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
Clofibrate activates Cypt2 through the PPARα pathway. Activation of PPARα by Clofibrate leads to downstream events that positively regulate Cypt2 expression and activity. This emphasizes the intricate connection between lipid metabolism and Cypt2 activation, offering potential strategies for therapeutic modulation by targeting the PPARα pathway as a means to influence Cypt2 function in various cellular contexts. | ||||||
KN-62 | 127191-97-3 | sc-3560 | 1 mg | $136.00 | 20 | |
KN-62 activates Cypt2 through the CaMKKβ-AMPK pathway. Inhibition of CaMKKβ by KN-62 leads to downstream signaling events that culminate in enhanced Cypt2 activation. This elucidates the intricate cross-talk between CaMKKβ-AMPK signaling and Cypt2 regulation, uncovering a potential avenue for therapeutic intervention by targeting specific nodes within the signaling cascade associated with Cypt2 activation. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $37.00 $112.00 $408.00 | ||
BIX 01294 indirectly activates Cypt2 by modulating histone methylation. Inhibition of histone methyltransferases by BIX 01294 influences chromatin structure, leading to enhanced Cypt2 expression and activity. This underscores the epigenetic control of Cypt2 activity, suggesting a potential strategy for manipulating its function through altering histone modification dynamics. | ||||||
GW 3965 hydrochloride | 405911-17-3 | sc-224011 sc-224011A sc-224011B | 5 mg 25 mg 1 g | $140.00 $483.00 $3121.00 | ||
GW3965 activates Cypt2 through the LXRα pathway. Activation of LXRα by GW3965 leads to downstream events that positively regulate Cypt2 expression and activity. This highlights the intricate connection between cholesterol metabolism and Cypt2 activation, offering potential strategies for therapeutic modulation by targeting the LXRα pathway as a means to influence Cypt2 function in various cellular contexts. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR activates Cypt2 through the AMPK pathway. Activation of AMPK by AICAR leads to downstream events that positively regulate Cypt2 expression and activity. This emphasizes the intricate connection between cellular energy sensing and Cypt2 activation, offering potential strategies for therapeutic modulation by targeting the AMPK pathway as a means to influence Cypt2 function in various cellular contexts. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 activates Cypt2 through the PI3K-AKT pathway. Inhibition of PI3K by LY294002 disrupts the negative regulation of AKT, leading to enhanced phosphorylation and activation of Cypt2. This unveils a direct link between PI3K-AKT signaling and Cypt2 activity, providing insights into potential therapeutic interventions targeting this pathway to modulate Cypt2 function in various cellular processes. | ||||||