Date published: 2025-10-3

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Cypin Activators

Cypin Activators is a chemical class that encompasses various compounds with the potential to directly or indirectly stimulate the activity of guanine deaminase, also known as Cypin. This enzyme plays a significant role in purine metabolism, catalyzing the conversion of guanine to xanthine, a process that results in the release of ammonia. Direct Cypin activators are compounds that can enhance the enzyme's activity by binding to it. This binding may either increase the enzyme's affinity for its natural substrate (guanine) or may stimulate the catalytic activity of the enzyme itself. Such activators often have structures similar to the natural substrate of the enzyme, which allows them to bind to the active site of the enzyme and increase its activity. On the other hand, indirect Cypin activators are compounds that increase the enzyme's activity by altering the concentration or availability of its substrates or products within the cell.

The indirect activators, in particular, can have complex effects due to their interaction with multiple components of the purine metabolic pathway. Despite this complexity, the study of Cypin activators provides valuable insights into the regulation of guanine deaminase and the broader purine metabolic pathway. This knowledge can expand our understanding of cellular metabolism and the intricate balance of enzymatic reactions that maintain cellular function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

AICAR, an intermediate in purine metabolism, may stimulate guanine deaminase (Cypin) indirectly by increasing substrate availability.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

MPA could indirectly promote guanine deaminase (Cypin) activity by inhibiting inosine monophosphate dehydrogenase and potentially increasing guanine concentrations.

Allopurinol

315-30-0sc-207272
25 g
$128.00
(0)

By inhibiting xanthine oxidase and potentially increasing xanthine concentrations, Allopurinol could indirectly spur guanine deaminase (Cypin) activity.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate may indirectly stimulate guanine deaminase (Cypin) activity by inhibiting dihydrofolate reductase and potentially influencing purine nucleotide synthesis.

Azathioprine

446-86-6sc-210853D
sc-210853
sc-210853A
sc-210853B
sc-210853C
500 mg
1 g
2 g
5 g
10 g
$199.00
$173.00
$342.00
$495.00
$690.00
1
(1)

Azathioprine, by being metabolized to 6-mercaptopurine (an inhibitor of purine synthesis), could indirectly stimulate guanine deaminase (Cypin) activity.

Febuxostat

144060-53-7sc-207680
10 mg
$168.00
3
(1)

Febuxostat could indirectly provoke guanine deaminase (Cypin) activity by inhibiting xanthine oxidase and potentially increasing xanthine concentrations.

6-Thioguanine

154-42-7sc-205587
sc-205587A
250 mg
500 mg
$41.00
$53.00
3
(1)

6-Thioguanine, a guanine analog, may indirectly stimulate guanine deaminase (Cypin) activity by potentially competing with guanine for binding.

Adenine, cell culture grade

73-24-5sc-291834
sc-291834A
sc-291834B
5 g
25 g
100 g
$82.00
$206.00
$546.00
2
(0)

As a purine base, Adenine could indirectly stimulate guanine deaminase (Cypin) activity by contributing to the pool of purine metabolites.

Hypoxanthine

68-94-0sc-29068
25 g
$68.00
3
(1)

Hypoxanthine, a key intermediate in purine metabolism, may indirectly spur guanine deaminase (Cypin) activity.

Adenosine

58-61-7sc-291838
sc-291838A
sc-291838B
sc-291838C
sc-291838D
sc-291838E
sc-291838F
1 g
5 g
100 g
250 g
1 kg
5 kg
10 kg
$33.00
$47.00
$294.00
$561.00
$1020.00
$2550.00
$4590.00
1
(0)

Being metabolized to inosine and hypoxanthine, Adenosine may indirectly stimulate guanine deaminase (Cypin) activity.