Febuxostat CAS: 144060-53-7
MF: C16H16N2O3S
MW: 316.37
An inhibitor xanthine oxidase and xanthine dehydrogenase.

Febuxostat (CAS 144060-53-7)

Febuxostat | CAS 144060-53-7 is rated 5.0 out of 5 by 1.
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Synonym: Adenuric; 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Application: An inhibitor xanthine oxidase and xanthine dehydrogenase
CAS Number: 144060-53-7
Purity: >99%
Molecular Weight: 316.37
Molecular Formula: C16H16N2O3S
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Febuxostat inhibits xanthine oxidase and xanthine dehydrogenase.


References

Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),

Physical State :
Solid
Solubility :
Soluble in DMSO
Storage :
Store at 4° C
Melting Point :
208-210° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
134018
SMILES :
CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O

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Certificate of Analysis

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Febuxostat  Product Citations

See how others have used Febuxostat. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25044064  Kim, NH. et al. 2014. European journal of immunology. 44: 2721-36.

Citations 1 to 1 of 1 total

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Febuxostat, sc-207680, is a white to light yellow powder.
Answered by: TechService7
Date published: 2017-02-09
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Rated 5 out of 5 by from Kramkowski K; et al Kramkowski K; et al. (PubMed ID: 26374946) determined that Febuxostat partially revered the anti-thrombotic effect of nitrite in rats. -SCBT Publication Review
Date published: 2015-05-23
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