CYP1B1 Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TMS | 24144-92-1 | sc-203708 sc-203708A | 10 mg 50 mg | $162.00 $417.00 | ||
TMS exhibits unique interactions with CYP1B1, characterized by its ability to form stable complexes through hydrogen bonding and hydrophobic interactions. Its structural conformation allows for effective substrate positioning, enhancing catalytic efficiency. The compound's reactivity is influenced by electron-donating groups, which modulate the enzyme's active site dynamics. Additionally, TMS demonstrates distinct reaction kinetics, showcasing a balance between substrate affinity and competitive inhibition, ultimately shaping metabolic pathways. | ||||||
Lumaricoxib | 220991-20-8 | sc-205736 sc-205736A | 100 mg 250 mg | $140.00 $280.00 | ||
Lumiracoxib is a nonsteroidal anti-inflammatory drug (NSAID) that has been studied for its potential to inhibit CYP1B1 activity. It competitively inhibits the enzyme, suggesting its potential for modulating CYP1B1 substrate metabolism. | ||||||
Alizarin | 72-48-0 | sc-214519 sc-214519A | 1.5 g 100 g | $21.00 $50.00 | ||
Alizarin interacts with CYP1B1 through specific π-π stacking and electrostatic interactions, facilitating its binding to the enzyme's active site. This compound exhibits unique conformational flexibility, allowing it to adapt to varying substrate environments, which influences its metabolic fate. The presence of functional groups alters the electron density, impacting the enzyme's catalytic activity. Alizarin's distinct kinetic profile reveals a nuanced interplay between substrate turnover and enzyme regulation, shaping its biochemical pathways. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Ellagic acid is a polyphenol found in fruits and nuts. It exhibits inhibitory effects on CYP1B1, potentially aiding in reducing the activation of procarcinogens and supporting chemoprevention. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $51.00 $77.00 $102.00 $153.00 $2856.00 | 7 | |
Fisetin is a naturally occurring polyphenol found in fruits and vegetables. It has demonstrated inhibitory effects on CYP1B1, which could help suppress the activation of procarcinogens. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane is a compound present in cruciferous vegetables like broccoli. Studies have explored its potential to inhibit CYP1B1, thereby reducing the bioactivation of specific carcinogens. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol in grapes, berries, and red wine, has been suggested to possess inhibitory properties against CYP1BThis could contribute to its potential as a chemopreventive agent. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid in various plant-based foods, can inhibit CYP1B1-mediated metabolism of certain procarcinogens. This action might lead to reduced activation of these compounds. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Found in cruciferous vegetables, indole-3-carbinol inhibits CYP1B1, potentially decreasing the activation of carcinogens and aiding in cancer prevention. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol, a phenolic compound in clove oil and other plants, exhibits potential as a CYP1B1 inhibitor. This effect could have implications for cancer prevention. | ||||||