Molecular structure of TMS, CAS Number: 24144-92-1
TMS (CAS 24144-92-1)
Alternate Names:
2,3',4,5'-Tetramethoxystilbene; 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene
Application:
TMS is an inhibitor of cytochrome P450 1B1 and cancer cell growth
CAS Number:
24144-92-1
Purity:
≥98%
Molecular Weight:
300.35
Molecular Formula:
C18H20O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TMS is a strong, selective and competitive inhibitor of cytochrome P450 1B1, an overexpressed enzyme in particular tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. TMS inhibits cancer cell growth in vitro.
TMS (CAS 24144-92-1) References
1. Nam, K.A., et al. 2001. Arch. Pharm. Res. 24: 441-445.2. Chun, Y.J., et al. 2001. Cancer Res. 61: 8164-8170.
3. Kim, S., et al. 2002. J. Med. Chem. 45: 160-164.
Inhibitor of:
CYP1A1, and CYP1B1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMS, 10 mg | sc-203708 | 10 mg | $162.00 | |||
TMS, 50 mg | sc-203708A | 50 mg | $417.00 |