CXCR-4 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AMD3100 octahydrochloride | 155148-31-5 | sc-252367 | 5 mg | $90.00 | 19 | |
AMD3100, also known as Plerixafor, is a known antagonist of CXCR-4 and can potentially down-regulate its expression in certain cells. | ||||||
AMD 3465 hexahydrobromide | 185991-07-5 | sc-362709 sc-362709A | 10 mg 50 mg | $185.00 $772.00 | ||
AMD 3465 hexahydrobromide acts as a potent CXCR-4 antagonist, showcasing remarkable affinity for the receptor through specific ionic interactions and hydrophobic contacts. Its unique stereochemistry promotes conformational flexibility, allowing it to effectively disrupt receptor dimerization and downstream signaling cascades. The compound's high solubility in polar solvents enhances its bioavailability, while its bromide substituents introduce distinctive reactivity, influencing its behavior in diverse biochemical contexts. | ||||||
TC 14012 | 368874-34-4 | sc-362800 sc-362800A sc-362800B | 1 mg 50 mg 100 mg | $199.00 $7500.00 $13500.00 | ||
TC 14012 functions as a selective CXCR-4 modulator, characterized by its ability to engage in specific hydrogen bonding and π-π stacking interactions with the receptor. This compound exhibits a unique conformational rigidity that stabilizes its binding, effectively inhibiting receptor activation. Its distinct electronic properties facilitate rapid reaction kinetics, while its solubility profile allows for versatile interactions in various biochemical environments, enhancing its functional versatility. | ||||||
WZ811 | 55778-02-4 | sc-296701 sc-296701A | 1 mg 5 mg | $29.00 $66.00 | ||
WZ811 is an effective CXCR-4 antagonist that might lead to receptor down-regulation by blocking its activation. | ||||||
FC 131 | 606968-52-9 | sc-362738 | 1 mg | $430.00 | ||
FC-131 is a CXCR-4 antagonist, which can potentially down-regulate the receptor in certain cell types. | ||||||
Plumbagin | 481-42-5 | sc-253283 sc-253283A | 100 mg 250 mg | $51.00 $61.00 | 6 | |
Plumbagin acts as a CXCR-4 modulator, showcasing a unique ability to form strong hydrophobic interactions and coordinate bonds with the receptor. Its planar structure promotes effective π-π interactions, enhancing binding affinity. The compound's dynamic conformational flexibility allows it to adapt to different receptor states, influencing downstream signaling pathways. Additionally, its lipophilic nature contributes to its distribution in cellular membranes, impacting its interaction dynamics within complex biological systems. | ||||||
MSX-122 | 897657-95-3 | sc-507328 | 50 mg | $690.00 | ||
MSX-122 is a partial CXCR-4 antagonist that can potentially reduce CXCR-4 levels in specific cells. | ||||||
Gambogic Acid | 2752-65-0 | sc-200137 sc-200137A sc-200137B sc-200137C sc-200137D | 5 mg 25 mg 100 mg 500 mg 1 g | $85.00 $243.00 $419.00 $720.00 $1230.00 | 5 | |
Gambogic Acid has been shown to down-regulate CXCR-4 expression, potentially reducing tumor metastasis. | ||||||
SR 48692 | 146362-70-1 | sc-363290 sc-363290A sc-363290B sc-363290C sc-363290D | 5 mg 25 mg 100 mg 500 mg 1 g | $156.00 $593.00 $2327.00 $10500.00 $20990.00 | 2 | |
SR 48692 is an antagonist of CXCR-4 that might reduce its levels in specific cells. | ||||||