MSX-122 (CAS 897657-95-3)
Alternate Names:
MSX122 MSX 122
CAS Number:
897657-95-3
Molecular Weight:
292.34
Molecular Formula:
C16H16N6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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MSX-122 (CAS 897657-95-3) References
- Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach. | Neves, MA., et al. 2010. J Comput Aided Mol Des. 24: 1023-33. PMID: 20960031
- Development of a unique small molecule modulator of CXCR4. | Liang, Z., et al. 2012. PLoS One. 7: e34038. PMID: 22485156
- Halting metastasis through CXCR4 inhibition. | Ramsey, DM. and McAlpine, SR. 2013. Bioorg Med Chem Lett. 23: 20-5. PMID: 23211868
- Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction. | Ziarek, JJ., et al. 2012. Curr Top Med Chem. 12: 2727-40. PMID: 23368099
- Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells. | Huang, MB., et al. 2018. Oncotarget. 9: 16996-17013. PMID: 29682200
- Synthesis and evaluation of 2,5-diamino and 2,5-dianilinomethyl pyridine analogues as potential CXCR4 antagonists. | Virani, S., et al. 2019. Bioorg Med Chem Lett. 29: 220-224. PMID: 30514601
- Microtiter plate-based antibody-competition assay to determine binding affinities and plasma/blood stability of CXCR4 ligands. | Harms, M., et al. 2020. Sci Rep. 10: 16036. PMID: 32994431
- CXCR4 promotes the growth and metastasis of esophageal squamous cell carcinoma as a critical downstream mediator of HIF-1α. | Wu, X., et al. 2022. Cancer Sci. 113: 926-939. PMID: 34990040
- CXCR4 antagonists disrupt leukaemia-meningeal cell adhesion and attenuate chemoresistance. | Jonart, LM., et al. 2023. Br J Haematol. 201: 459-469. PMID: 36535585
- N-Alkylation of Amines by C1-C10 Aliphatic Alcohols Using A Well-Defined Ru(II)-Catalyst. A Metal-Ligand Cooperative Approach. | Guin, AK., et al. 2023. J Org Chem.. PMID: 37052217
Inhibitor of:
CA X, CXCR-4, HES1, IL-8RB, and RDC-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MSX-122, 50 mg | sc-507328 | 50 mg | $690.00 |