CTAGE2 Activators
CTAGE2 Activators are chemicals that can enhance the functional activity of CTAGE2 through specific signaling pathways that CTAGE2 is directly involved in. All the chemicals listed here either activate SIRT1, inhibit the PI3K/AKT pathway, inhibit the mTOR pathway, or inhibit the MAPK pathway, which can lead to the activation of FOXO3a and subsequently enhance the transcription of CTAGE2. Resveratrol is known to activate SIRT1, which can deacetylate FOXO3a.
Deacetylated FOXO3a can translocate to the nucleus and activate the transcription of CTAGE2. Berberine and Metformin can inactivate the mTOR pathway or directly activate AMPK, leading to the activation of FOXO3a, and subsequently enhance the transcription of CTAGE2. AICAR also activates AMPK, leading to FOXO3a activation and subsequent enhancement of CTAGE2 transcription. On the other hand, chemicals like Quercetin, Wogonin, Curcumin, Genistein, EGCG, LY294002, PD98059, and U0126 inhibit the PI3K/AKT pathway or the MAPK pathway, which enhances FOXO3a activity. Activated FOXO3a can promote the transcription of CTAGE2.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can activate SIRT1, which deacetylates FOXO3a. Deacetylated FOXO3a can translocate to the nucleus and activate the transcription of CTAGE2. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can inhibit PI3K/AKT pathway, leading to the activation of FOXO3a. Activated FOXO3a can promote the transcription of CTAGE2. | ||||||
Wogonin, S. baicalensis | 632-85-9 | sc-203313 | 10 mg | $200.00 | 8 | |
Wogonin can inhibit the PI3K/AKT pathway, enhancing the activity of FOXO3a. The activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine can inactivate the mTOR pathway, activating AMPK. AMPK can then activate FOXO3a, which may enhance the transcription of CTAGE2. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $292.00 $822.00 $1540.00 | 1 | |
Metformin can activate AMPK, leading to the activation of FOXO3a. Activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR can activate AMPK, leading to the activation of FOXO3a. Activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can inhibit the PI3K/AKT pathway, enhancing the activity of FOXO3a. The activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can inhibit the PI3K/AKT pathway, enhancing the activity of FOXO3a. The activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can inhibit the PI3K/AKT pathway, enhancing the activity of FOXO3a. The activated FOXO3a can enhance the transcription of CTAGE2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 can inhibit the PI3K/AKT pathway, enhancing the activity of FOXO3a. The activated FOXO3a can enhance the transcription of CTAGE2. | ||||||