COL18A1 Activators
The chemical class of COL18A1 Activators encompasses various compounds that can indirectly stimulate or modulate the synthesis and stability of Collagen alpha-1(XVIII) chain, a key component of the extracellular matrix with roles in angiogenesis and tumor suppression. This class includes essential nutrients and vitamins, like Ascorbic Acid (Vitamin C), which is crucial for collagen synthesis, and Retinoic Acid, known for its role in skin health and influence on extracellular matrix composition. The inclusion of copper sulfate highlights the importance of cofactors in collagen synthesis and crosslinking.
Additionally, this class incorporates phytochemicals and natural compounds with antioxidant properties, such as Genistein, Epigallocatechin Gallate (EGCG), Curcumin, Tannic Acid, Ellagic Acid, and Resveratrol. These compounds, through their various effects on cellular pathways, can potentially enhance the synthesis and stability of COL18A1. The role of essential amino acids like Lysine, Proline, and Glycine is also emphasized, as they are integral to collagen structure and stability, potentially affecting COL18A1 production.
SEE ALSO...
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Essential for collagen synthesis, ascorbic acid can enhance the stability and production of collagen, potentially including COL18A1. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in skin health and collagen synthesis, retinoic acid can influence extracellular matrix composition and may indirectly upregulate COL18A1. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper is a cofactor for lysyl oxidase, an enzyme involved in collagen crosslinking. Enhancing copper levels can indirectly affect collagen stability and synthesis, including COL18A1. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A phytoestrogen with antioxidant properties, genistein can influence extracellular matrix components and potentially enhance COL18A1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound in turmeric, curcumin can modulate various cellular pathways, including those related to extracellular matrix regulation, potentially influencing COL18A1 synthesis. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Known for its astringent properties, tannic acid can influence extracellular matrix components and may indirectly enhance COL18A1 synthesis. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A polyphenol with antioxidant properties, ellagic acid can influence extracellular matrix and angiogenesis, potentially affecting COL18A1 synthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A stilbenoid found in grapes, resveratrol can modulate pathways related to cellular aging and extracellular matrix composition, potentially influencing COL18A1. | ||||||
L-Lysine | 56-87-1 | sc-207804 sc-207804A sc-207804B | 25 g 100 g 1 kg | $95.00 $263.00 $529.00 | ||
An essential amino acid important for collagen synthesis, lysine supplementation can potentially enhance COL18A1 production. | ||||||
L-Proline | 147-85-3 | sc-397196 sc-397196A sc-397196B sc-397196C | 25 g 100 g 1 kg 5 kg | $38.00 $133.00 $208.00 $978.00 | ||
Another amino acid crucial for collagen stability, proline can influence collagen synthesis, potentially affecting COL18A1. | ||||||