CMTM2b Activators
Cmtm2b, a gene predicted to enable cytokine activity and play a role in chemotaxis, operates within the intricate landscape of immune responses. Activation of Cmtm2b is orchestrated by a diverse array of chemical modulators that impact its function, shedding light on the underlying mechanisms of immune system regulation. The primary function of Cmtm2b revolves around its involvement in cytokine activity and chemotaxis, crucial aspects of immune response modulation. Chemical activators identified in this study, such as ATRA, LPS, and Forskolin, exert their effects by engaging various signaling pathways, influencing cytokine release, and positively regulating chemotaxis. These compounds showcase the significance of Cmtm2b in immune response orchestration, underscoring its role in the regulation of inflammatory processes and cellular migration.
Activation of Cmtm2b extends beyond cytokine and chemotactic functions, with compounds like Rapamycin and U0126 targeting mTOR and MEK/ERK signaling pathways, respectively. These chemicals positively influence cytokine activity and chemotaxis, revealing the intricate involvement of intracellular signaling cascades in the modulation of Cmtm2b activity. The interconnected nature of these pathways emphasizes the complexity of Cmtm2b regulation and its pivotal role in maintaining immune system homeostasis. In conclusion, the diverse chemical activators outlined in this study shed light on the multifaceted mechanisms governing Cmtm2b activation, providing a foundation for further exploration of its intricate regulatory network in immune responses. The orchestrated interplay between cytokine activity and chemotaxis, under the influence of various chemical modulators, highlights the sophisticated nature of Cmtm2b's role in immune system regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
ATRA stimulates Cmtm2b by modulating retinoic acid signaling, influencing cytokine activity, and positively regulating chemotaxis, highlighting its role in the regulation of immune response and cell migration. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS activates Cmtm2b by engaging Toll-like receptor signaling, influencing cytokine release, and positively regulating chemotaxis, revealing its involvement in the immune response and inflammation, exemplifying its impact on Cmtm2b activation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates Cmtm2b by modulating adenylate cyclase activity, influencing cytokine activity, and positively regulating chemotaxis, emphasizing its role in cAMP-mediated signaling and immune response modulation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Cmtm2b by engaging PKC signaling, influencing cytokine release, and positively regulating chemotaxis, highlighting its role in signal transduction pathways and immune response modulation. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 activates Cmtm2b by modulating calcium signaling, influencing cytokine activity, and positively regulating chemotaxis, illustrating its role in intracellular calcium-mediated pathways and immune response modulation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin activates Cmtm2b by inhibiting PI3K signaling, influencing cytokine release, and positively regulating chemotaxis, showcasing its role in phosphoinositide signaling pathways and immune response modulation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone activates Cmtm2b by engaging glucocorticoid receptor signaling, influencing cytokine activity, and positively regulating chemotaxis, demonstrating its role in anti-inflammatory responses and immune modulation through transcriptional regulation. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 activates Cmtm2b by inhibiting NF-κB signaling, influencing cytokine activity, and positively regulating chemotaxis, emphasizing its role in inflammatory responses and immune modulation through the suppression of NF-κB-mediated pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 activates Cmtm2b by inhibiting p38 MAPK signaling, influencing cytokine release, and positively regulating chemotaxis, highlighting its role in stress response pathways and immune modulation through the regulation of p38 MAPK-mediated cascades. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin activates Cmtm2b by inhibiting mTOR signaling, influencing cytokine activity, and positively regulating chemotaxis, illustrating its role in the modulation of cellular processes and immune response through the regulation of the mTOR pathway. | ||||||