CMTM2a Inhibitors
CMTM2a, an integral player in transcription corepressor activity, orchestrates cellular processes in the cytoplasm and nucleus. Actinomycin D, a potent RNA polymerase inhibitor, directly targets CMTM2a, disrupting its involvement in negative regulation of transcription and testosterone biosynthetic processes. Trichostatin A and SAHA modulate CMTM2a's transcription corepressor activity, influencing cellular dynamics in critical cellular compartments.
Etoposide and Camptothecin, inhibitors of topoisomerases, directly impact CMTM2a, disrupting its role in transcription corepressor activity and influencing processes related to testosterone biosynthesis. Flavopiridol and Vorinostat provide insights into CMTM2a's modulation through cyclin-dependent kinase and histone deacetylase inhibition, respectively. The DNA intercalators Doxorubicin and Ellipticine, along with the crosslinking agent Cisplatin, target CMTM2a, influencing its transcription corepressor activity and the regulation of testosterone biosynthesis. Azacitidine and 5-Aza-2'-deoxycytidine, DNA methyltransferase inhibitors, serve as direct CMTM2a inhibitors, providing a comprehensive understanding of the regulatory mechanisms involved in transcription and testosterone biosynthesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D, an RNA polymerase inhibitor, directly targets CMTM2a by preventing transcription. This inhibition disrupts CMTM2a's role in negative regulation of transcription, DNA-templated and regulation of the testosterone biosynthetic process, impacting cellular processes in the cytoplasm and nucleus. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, serves as a direct inhibitor of CMTM2a by modulating transcription corepressor activity. This interference disrupts CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular dynamics in the cytoplasm and nucleus. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide, a topoisomerase II inhibitor, directly targets CMTM2a, influencing its transcription corepressor activity. This disruption impacts CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular processes in the cytoplasm and nucleus. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
SAHA, also known as Vorinostat, a histone deacetylase inhibitor, serves as a direct CMTM2a inhibitor by modulating transcription corepressor activity. This interference disrupts CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, influencing cellular dynamics in the cytoplasm and nucleus. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin, a DNA topoisomerase I inhibitor, directly targets CMTM2a, impacting its transcription corepressor activity. This disruption influences CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular processes in the cytoplasm and nucleus. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol, a cyclin-dependent kinase inhibitor, serves as a direct CMTM2a inhibitor by modulating transcription corepressor activity. This interference disrupts CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, influencing cellular dynamics in the cytoplasm and nucleus. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin, a DNA intercalator and topoisomerase II inhibitor, directly targets CMTM2a, impacting its transcription corepressor activity. This disruption influences CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular processes in the cytoplasm and nucleus. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Cisplatin, a DNA crosslinking agent, directly targets CMTM2a, impacting its transcription corepressor activity. This disruption influences CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular processes in the cytoplasm and nucleus. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine, a DNA methyltransferase inhibitor, serves as a direct CMTM2a inhibitor by modulating transcription corepressor activity. This interference disrupts CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, influencing cellular dynamics in the cytoplasm and nucleus. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
Ellipticine, a DNA intercalator and topoisomerase II inhibitor, directly targets CMTM2a, impacting its transcription corepressor activity. This disruption influences CMTM2a-mediated negative regulation of transcription and regulation of testosterone biosynthetic processes, affecting cellular processes in the cytoplasm and nucleus. | ||||||