Date published: 2026-4-20

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CLC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. CLC gene silencers are available as CLC CRISPR/Cas9 Knockout plasmids and CLC Double Nickase Plasmids. CLC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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CLC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLC-KA Double Nickase Plasmid (h)

sc-404050-NIChGene KnockoutPuromycin0
(0)

CLC-KA Double Nickase Plasmid (h2)

sc-404050-NIC-2hGene KnockoutPuromycin0
(0)

CLC-1 CRISPR/Cas9 KO Plasmid (h)

sc-405071hGene KnockoutGFP0
(0)

CLC-1 Double Nickase Plasmid (h)

sc-405071-NIChGene KnockoutPuromycin0
(0)

CLC-1 Double Nickase Plasmid (h2)

sc-405071-NIC-2hGene KnockoutPuromycin0
(0)

CLC-2 Double Nickase Plasmid (h)

sc-403513-NIChGene KnockoutPuromycin0
(0)

CLC-2 Double Nickase Plasmid (h2)

sc-403513-NIC-2hGene KnockoutPuromycin0
(0)

CLC-3 Double Nickase Plasmid (h)

sc-402781-NIChGene KnockoutPuromycin0
(0)

CLC-3 Double Nickase Plasmid (h2)

sc-402781-NIC-2hGene KnockoutPuromycin0
(0)

CLC-3 CRISPR/Cas9 KO Plasmid (m)

sc-419677mGene KnockoutGFP0
(0)

CLC-3 HDR Plasmid (m)

sc-419677-HDRmHomology Directed RepairPuromycin0
(0)

CLC-5 CRISPR/Cas9 KO Plasmid (h)

sc-404859hGene KnockoutGFP0
(0)

CLC-5 HDR Plasmid (h)

sc-404859-HDRhHomology Directed RepairPuromycin0
(0)

CLC-5 Double Nickase Plasmid (h)

sc-404859-NIChGene KnockoutPuromycin0
(0)

CLC-5 Double Nickase Plasmid (h2)

sc-404859-NIC-2hGene KnockoutPuromycin0
(0)

CLC-6 CRISPR/Cas9 KO Plasmid (h)

sc-405938hGene KnockoutGFP0
(0)

CLC-6 Double Nickase Plasmid (h)

sc-405938-NIChGene KnockoutPuromycin0
(0)

CLC-6 Double Nickase Plasmid (h2)

sc-405938-NIC-2hGene KnockoutPuromycin0
(0)

CLC-7 CRISPR/Cas9 KO Plasmid (h)

sc-404550hGene KnockoutGFP0
(0)

CLC-7 Double Nickase Plasmid (h)

sc-404550-NIChGene KnockoutPuromycin0
(0)

CLC-7 Double Nickase Plasmid (h2)

sc-404550-NIC-2hGene KnockoutPuromycin0
(0)

CLC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CLC-KA CRISPR Activation Plasmid (h)

sc-404050-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLC-1 CRISPR Activation Plasmid (h)

sc-405071-ACThGene ActivationPuro, Blast, Hygro0
(0)

CLC-2 CRISPR Activation Plasmid (h)

sc-403513-ACThGene ActivationPuro, Blast, Hygro0
(0)