Chromozym PL Activators
Chromozym PL Activators encompass a variety of chemical compounds that influence specific cellular pathways, indirectly promoting the functional activity of Chromozym PL. For instance, compounds such as 1-oleoyl-2-acetyl-sn-glycerol (OAG) and Phorbol 12-myristate 13-acetate (PMA) specifically activate protein kinase C (PKC), which can phosphorylate proteins that are either part of Chromozym PL's signaling cascade or that modulate its activity, leading to an enhancement of Chromozym PL's functional role.
Additionally, agents that alter intracellular calcium concentrations, including Ionomycin and A23187, act as calcium ionophores to initiate calcium-dependent signaling mechanisms, which may also culminate in the amplification of Chromozym PL's biochemical processes. Similarly, Forskolin and IBMX, through the elevation of cyclic AMP (cAMP) and subsequent activation of protein kinase A (PKA), as well as Dibutyryl-cAMP (db-cAMP), a cAMP analog, can facilitate the activation of Chromozym PL via phosphorylation events.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1-Oleoyl-2-acetyl-sn-glycerol (OAG) | 86390-77-4 | sc-200417 sc-200417A | 10 mg 50 mg | $119.00 $453.00 | 1 | |
OAG is a diacylglycerol analog that activates protein kinase C (PKC). PKC activation can enhance Chromozym PL activity by phosphorylation of downstream proteins that may interact with or modulate Chromozym PL. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent PKC activator. By activating PKC, it can increase the phosphorylation of proteins in pathways where Chromozym PL is involved, thereby enhancing Chromozym PL's functional activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that raises intracellular calcium levels, activating calcium-dependent kinases and phosphatases, which may lead to the enhanced activity of Chromozym PL through downstream effects. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels, which in turn can activate PKA. PKA may phosphorylate substrates that interact with or modulate Chromozym PL, leading to its enhanced activity. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterases, leading to increased cAMP levels, which can activate PKA and potentially enhance Chromozym PL activity through downstream signaling events. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that leads to increased cytosolic calcium levels, potentially activating calcium-dependent signaling pathways that could enhance Chromozym PL activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is a calcium ionophore, similar to ionomycin, and can similarly enhance Chromozym PL activity by increasing intracellular calcium and activating calcium-dependent signaling pathways. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
BIM I is a PKC inhibitor. Paradoxically, chronic inhibition of PKC can lead to a compensatory increase in PKC activity in some cells, which might indirectly enhance Chromozym PL activity. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is a protein phosphatase inhibitor. By inhibiting phosphatases, it could lead to increased phosphorylation levels of proteins within Chromozym PL's signaling pathways, enhancing its activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Similar to Calyculin A, okadaic acid inhibits protein phosphatases 1 and 2A, potentially increasing phosphorylation and activity of proteins that regulate Chromozym PL activity. | ||||||