Ces3b Inhibitors
Ces3b, a gene predicted to encode methyl indole-3-acetate esterase activity and located in the endoplasmic reticulum, serves a pivotal role in cellular processes. Its predicted function implies a key involvement in the hydrolysis of specific substrates, particularly indole-3-acetate, suggesting its essential contribution to cellular homeostasis and metabolic pathways. Positioned within the endoplasmic reticulum, Ces3b likely plays a critical role in regulating intracellular processes, with a particular focus on the metabolism of indole-3-acetate, a molecule with potential signaling and regulatory functions in cellular responses.
The inhibition of Ces3b encompasses a spectrum of strategies, both direct and indirect, aimed at modulating its enzymatic activity and cellular functions. Direct inhibition involves compounds that specifically target the active site of Ces3b, disrupting its methyl indole-3-acetate esterase activity. These inhibitors interfere with the catalytic function of Ces3b, potentially altering its substrate specificity or enzymatic efficiency. On the other hand, indirect inhibition relies on compounds that impact Ces3b through broader cellular pathways or processes. These modulators can influence Ces3b by altering cellular signaling cascades, disrupting endoplasmic reticulum localization, or indirectly affecting its functional integrity. The diversity of these inhibition mechanisms highlights the intricate regulatory network in which Ces3b operates, offering insights into the complex interplay of cellular processes involving indole-3-acetate metabolism and beyond. Understanding these intricate mechanisms of Ces3b inhibition not only contributes to unraveling the gene's functional significance but also provides a foundation for exploring potential regulatory strategies within cellular processes related to indole-3-acetate metabolism and beyond.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
Inhibitor targeting Ces3b by binding to its active site, hindering methyl indole-3-acetate esterase activity. Influences Ces3b localization in the endoplasmic reticulum, disrupting its functional integrity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Modulator impacting Ces3b indirectly by inhibiting related pathways. Alters cellular signaling cascades and influences Ces3b function, disrupting methyl indole-3-acetate esterase activity and affecting endoplasmic reticulum localization. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Calcium channel blocker that indirectly modulates Ces3b by affecting intracellular calcium levels. Disrupts methyl indole-3-acetate esterase activity and influences Ces3b localization in the endoplasmic reticulum, impacting its functional role. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
HMG-CoA reductase inhibitor influencing Ces3b indirectly through mevalonate pathway regulation. Alters protein prenylation, disrupting methyl indole-3-acetate esterase activity and impacting Ces3b localization in the endoplasmic reticulum. | ||||||
Triclosan | 3380-34-5 | sc-220326 sc-220326A | 10 g 100 g | $138.00 $400.00 | ||
Antimicrobial agent impacting Ces3b by disrupting cell membrane integrity. Alters cellular homeostasis, indirectly affecting methyl indole-3-acetate esterase activity and influencing Ces3b localization in the endoplasmic reticulum. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Calcium channel blocker indirectly influencing Ces3b by modulating intracellular calcium levels. Disrupts methyl indole-3-acetate esterase activity and affects Ces3b localization in the endoplasmic reticulum, impacting its functional role. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Antibiotic impacting Ces3b indirectly through gene expression regulation. Modulates cellular processes, disrupting methyl indole-3-acetate esterase activity and influencing Ces3b localization in the endoplasmic reticulum, altering its functional role. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
PPAR-α agonist indirectly modulating Ces3b through lipid metabolism pathways. Alters gene expression, disrupting methyl indole-3-acetate esterase activity and influencing Ces3b localization in the endoplasmic reticulum, impacting its functional role. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Mitochondrial complex I inhibitor indirectly influencing Ces3b through cellular energy metabolism. Disrupts methyl indole-3-acetate esterase activity and impacts Ces3b localization in the endoplasmic reticulum, altering its functional role. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $60.00 $108.00 | 21 | |
Neuroleptic drug indirectly impacting Ces3b through neurotransmitter modulation. Alters signaling cascades, disrupting methyl indole-3-acetate esterase activity and influencing Ces3b localization in the endoplasmic reticulum, impacting its functional role. | ||||||