Cell Signaling
Items 261 to 270 of 496 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bilirubin | 635-65-4 | sc-202499A sc-202499 sc-202499B sc-202499C sc-202499D | 100 mg 1 g 5 g 10 g 25 g | $114.00 $390.00 $1460.00 $2100.00 $4125.00 | 1 | |
Bilirubin serves as a significant signaling molecule, primarily involved in the regulation of oxidative stress responses. It interacts with various cellular receptors, modulating pathways linked to inflammation and apoptosis. Its antioxidant properties enable it to scavenge free radicals, thereby influencing cellular redox states. Furthermore, bilirubin can affect gene expression by altering the activity of transcription factors, contributing to the fine-tuning of cellular responses to environmental changes. | ||||||
SJ 172550 | 431979-47-4 | sc-357403 sc-357403A | 10 mg 50 mg | $175.00 $737.00 | 1 | |
SJ 172550 functions as a selective inhibitor in cell signaling by modulating the activity of specific kinases involved in phosphorylation cascades. It exhibits a unique ability to disrupt the binding of ATP to target enzymes, thereby altering downstream signaling pathways. This compound influences cellular responses by affecting the phosphorylation state of critical proteins, which can lead to changes in gene expression and cellular behavior. Its distinct interaction profile offers valuable insights into kinase regulation and signal transduction mechanisms. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $143.00 $510.00 | 2 | |
U 18666A is a notable compound in cell signaling, particularly influencing lipid metabolism and cellular stress responses. It interacts with specific membrane proteins, disrupting cholesterol transport and impacting lipid raft formation. This alteration can modulate signaling pathways related to cell survival and apoptosis. Additionally, U 18666A's unique ability to influence calcium signaling and reactive oxygen species production highlights its role in cellular homeostasis and stress adaptation. | ||||||
JNK3 Inhibitor XII | 1164153-22-3 | sc-364742 | 5 mg | $165.00 | ||
JNK3 Inhibitor XII acts as a potent modulator of cell signaling by selectively targeting the JNK3 pathway, influencing the phosphorylation of key substrates. Its unique binding affinity alters the conformational dynamics of the JNK3 enzyme, impacting the kinetics of signal propagation. By disrupting specific protein-protein interactions, it fine-tunes cellular responses, providing a deeper understanding of the regulatory networks governing cellular functions and stress responses. | ||||||
GSK 2334470 | 1227911-45-6 | sc-364501 sc-364501A | 10 mg 50 mg | $199.00 $1165.00 | 1 | |
GSK 2334470 functions as a selective modulator of cell signaling by engaging with specific kinases involved in the MAPK pathway. Its unique interaction profile promotes alterations in downstream signaling cascades, enhancing or inhibiting the phosphorylation of target proteins. This compound exhibits distinct reaction kinetics, allowing for precise temporal control of signaling events. By influencing molecular conformations, it provides insights into the intricate regulatory mechanisms of cellular communication. | ||||||
Terfenadine | 50679-08-8 | sc-208421A sc-208421B sc-208421 | 500 mg 1 g 5 g | $44.00 $71.00 $120.00 | ||
Terfenadine functions in cell signaling by selectively antagonizing histamine H1 receptors, which modulates downstream signaling pathways. Its unique structure facilitates specific interactions with receptor binding sites, influencing the activation of G proteins and subsequent intracellular signaling cascades. This selective binding alters calcium ion flux and phospholipase activity, ultimately affecting cellular responses and contributing to the regulation of various physiological processes. | ||||||
(−)-Isoproterenol (+)-bitartrate salt | 54750-10-6 | sc-252926 sc-252926A sc-252926D sc-252926B sc-252926C | 100 mg 500 mg 1 g 5 g 10 g | $105.00 $262.00 $413.00 $2341.00 $4474.00 | ||
(-)-Isoproterenol (+)-bitartrate salt acts as a potent agonist for beta-adrenergic receptors, initiating a cascade of intracellular signaling events. Its stereochemistry enhances affinity for these receptors, promoting the activation of adenylate cyclase and increasing cyclic AMP levels. This elevation in cyclic AMP modulates protein kinase activity, influencing metabolic pathways and cellular responses, such as smooth muscle relaxation and enhanced cardiac contractility. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $114.00 $525.00 | 4 | |
Indirubin is a notable compound in cell signaling, primarily recognized for its role in modulating the activity of various kinases, particularly cyclin-dependent kinases. By selectively inhibiting these enzymes, it influences cell cycle progression and differentiation. Additionally, Indirubin interacts with transcription factors, altering gene expression patterns that govern cellular responses. Its unique ability to traverse cellular membranes facilitates its engagement in diverse signaling pathways, impacting cellular homeostasis and function. | ||||||
Artemether | 71963-77-4 | sc-291911 sc-291911A sc-291911B sc-291911C sc-291911D | 5 g 25 g 100 g 1 kg 10 kg | $62.00 $230.00 $765.00 $2040.00 $18360.00 | 5 | |
Artemether exhibits unique interactions with cellular signaling pathways, particularly through its modulation of calcium ion channels. By influencing the release of intracellular calcium, it alters the dynamics of various signaling cascades. This compound also engages with specific G-proteins, leading to the activation of phospholipase C, which subsequently increases inositol trisphosphate levels. These interactions can significantly impact cellular processes, including gene expression and apoptosis. | ||||||
Clotrimazole | 23593-75-1 | sc-3583 sc-3583A | 100 mg 1 g | $42.00 $57.00 | 6 | |
Clotrimazole exhibits intriguing properties in cell signaling by modulating ion channel activity and influencing membrane fluidity. Its interaction with phospholipid bilayers alters the dynamics of lipid organization, which can affect receptor localization and downstream signaling cascades. This compound also engages in specific protein interactions that can disrupt normal cellular communication, potentially leading to altered responses in various signaling pathways, including those governing inflammation and cellular stress. | ||||||