Molecular structure of JNK3 Inhibitor XII, CAS Number: 1164153-22-3
JNK3 Inhibitor XII (CAS 1164153-22-3)
Alternate Names:
SR-3576; Aminopyrazole inhibitor, 3576; SR3576; SR 3576
Application:
JNK3 Inhibitor XII is a JNK3 and JNK1 inhibitor
CAS Number:
1164153-22-3
Purity:
≥98%
Molecular Weight:
501.5
Molecular Formula:
C27H27N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
JNK3 Inhibitor XII is a cell-permeable pyrazolourea compound that acts as a potent, ATP binding pocket-targeting, and JNK3-selective inhibitor (IC50 = 7 nM), inhibiting JNK1 only at much higher concentrations (IC50 = 170 nM) and exhibiting little activity against p38 even at concentrations as high as 20 µM. JNK3 Inhibitor XII is shown to inhibit streptozotocin- (sc-200719) induced c-Jun phosphorylation in INS-1 rat β-pancreatic cells (IC50 = 1.3 µM).
Inhibitor of:
JNK1, JNK3, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JNK3 Inhibitor XII, 5 mg | sc-364742 | 5 mg | $165.00 |