Molecular structure of Bilirubin, CAS Number: 635-65-4
Bilirubin (CAS 635-65-4)
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Alternate Names:
Hematoidin; Bilirubin IX-alpha; Hemetoidin; Principal bile pigment
Application:
Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition
CAS Number:
635-65-4
Molecular Weight:
584.66
Molecular Formula:
C33H36N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. Serves as a physiological antioxidant. Reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This product corresponds to the unconjugated form. Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
Bilirubin (CAS 635-65-4) References
- Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance. | Kamisako, T., et al. 2000. J Gastroenterol. 35: 659-64. PMID: 11023036
- Biological properties and therapeutic potential of bilirubin. | McGeary, RP., et al. 2003. Mini Rev Med Chem. 3: 253-6. PMID: 12570840
- Toward an amphiphilic bilirubin: the crystal structure of a bilirubin e-isomer. | Dey, SK. and Lightner, DA. 2008. J Org Chem. 73: 2704-14. PMID: 18327950
- Bilirubin diglucuronide as the main source for in vitro formation of delta bilirubin. | Adachi, Y., et al. 1991. J Clin Lab Anal. 5: 331-4. PMID: 1941353
- The biliverdin-bilirubin antioxidant cycle of cellular protection: Missing a wheel? | McDonagh, AF. 2010. Free Radic Biol Med. 49: 814-20. PMID: 20547221
- The status of bilirubin measurements in U.S. laboratories: why is accuracy elusive? | Lo, SF. and Doumas, BT. 2011. Semin Perinatol. 35: 141-7. PMID: 21641487
- The molecular basis for the immunomodulatory activities of unconjugated bilirubin. | Jangi, S., et al. 2013. Int J Biochem Cell Biol. 45: 2843-51. PMID: 24144577
- Bilirubin degradation in methanol induced by continuous UV-B irradiation: a UHPLC--ESI-MS study. | Stanojević, JS., et al. 2015. Pharmazie. 70: 225-30. PMID: 26012251
- In Vitro Evaluation of a Novel Synthetic Bilirubin Analog as an Antioxidant and Cytoprotective Agent for Pancreatic Islet Transplantation. | Luckring, EJ., et al. 2020. Cell Transplant. 29: 963689720906417. PMID: 32323568
- Investigation of mutations (L41F, F17M, N57E, Y99F_Y134W) effects on the TolAIII-UnaG fluorescence protein's unconjugated bilirubin (UC-BR) binding ability and thermal stability properties. | Eczacioglu, N., et al. 2022. Prep Biochem Biotechnol. 52: 365-374. PMID: 34319856
- Reserve bilirubin binding capacity assessed by difference spectroscopy: assay statistics and results on newborn sera. | Ash, KO., et al. 1980. Clin Chim Acta. 104: 309-18. PMID: 7389140
- Structure, formation, and sources of bilirubin and its transport in plasma. | . 1994. Semin Liver Dis. 14: 325-30. PMID: 7855626
- Increased plasma bilirubin in Parkinson patients on L-dopa: evidence against the free radical hypothesis? | Scigliano, G., et al. 1997. Ital J Neurol Sci. 18: 69-72. PMID: 9239525
- Heme oxygenase induction by UVA radiation. A response to oxidative stress in rat liver. | Ossola, JO. and Tomaro, ML. 1998. Int J Biochem Cell Biol. 30: 285-92. PMID: 9608682
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bilirubin, 100 mg | sc-202499A | 100 mg | $90.00 | |||
Bilirubin, 1 g | sc-202499 | 1 g | $310.00 | |||
Bilirubin, 5 g | sc-202499B | 5 g | $726.00 | |||
Bilirubin, 10 g | sc-202499C | 10 g | $1400.00 | |||
Bilirubin, 25 g | sc-202499D | 25 g | $2700.00 |