Cdx1 Activators
The chemical class known as Cdx1 Activators encompasses a diverse group of compounds that indirectly influence the activity of the Cdx1 protein. These chemicals primarily function by modulating various cellular signaling pathways that have downstream effects on Cdx1. For instance, Retinoic Acid and All-trans retinal, derivatives of Vitamin A, play pivotal roles in developmental processes and gene expression regulation. They modulate the Hox genes, which are intricately connected to Cdx1, thereby exerting an indirect influence on its activity. Similarly, Dihydrotestosterone and Lithium Chloride affect the Wnt/β-catenin pathway, crucial for embryonic development and known to interact with Cdx1. Inhibition of GSK-3β by Lithium Chloride leads to β-catenin stabilization, impacting Cdx1.
Other members of this class, such as Forskolin, Vismodegib, Biochanin A, Quercetin, Genistein, Curcumin, EGCG, and Sulforaphane, operate through varied mechanisms. Forskolin, by elevating cAMP levels, and Vismodegib, by inhibiting the Hedgehog pathway, demonstrate the diversity in the action of these compounds. Each of these chemicals affects different cellular signaling cascades such as adenylate cyclase activity, hedgehog signaling, flavonoid-mediated modulation, isoflavone-based interference, and antioxidant pathways. These cascades intersect with the network of pathways involving Cdx1, thereby influencing its activity indirectly.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of Vitamin A, retinoic acid plays a crucial role in body axis development. It modulates the expression of Hox genes, which are closely related to Cdx1 in the developmental process. By influencing Hox gene expression, retinoic acid can indirectly affect Cdx1 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Commonly used in Wnt pathway studies, Lithium Chloride inhibits GSK-3β, a negative regulator of the Wnt/β-catenin pathway. This inhibition can lead to the stabilization and accumulation of β-catenin, which can influence Cdx1 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
An activator of adenylate cyclase, Forskolin raises intracellular cAMP levels. Elevated cAMP can affect various signaling pathways that interact with Cdx1, potentially influencing its activity. | ||||||
Vismodegib | 879085-55-9 | sc-396759 sc-396759A | 10 mg 25 mg | $80.00 $96.00 | 1 | |
An inhibitor of the Hedgehog signaling pathway, Vismodegib can indirectly influence Cdx1 activity by modulating the pathway, which has cross-talk with pathways involving Cdx1. | ||||||
all-trans Retinal | 116-31-4 | sc-210778A sc-210778 | 250 mg 1 g | $126.00 $372.00 | 7 | |
An aldehyde form of Vitamin A, it is involved in the visual cycle but also plays a role in gene expression regulation. It may affect pathways related to Cdx1 activity. | ||||||
Biochanin A | 491-80-5 | sc-205603 sc-205603A | 100 mg 250 mg | $75.00 $129.00 | ||
A natural organic compound, known to modulate various signaling pathways, including those related to Cdx1. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid with antioxidant properties, it influences multiple signaling pathways, potentially impacting Cdx1 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone, known to modulate cellular signaling pathways that could intersect with Cdx1's regulatory network. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A component of turmeric, known to modulate various cellular processes and pathways that may interact with Cdx1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A major component of green tea, known for its influence on multiple signaling pathways. It may indirectly impact Cdx1 activity. | ||||||