The class of CDC14 activators encompasses a diverse set of compounds that could potentially influence the function or regulation of CDC14 indirectly. This can be achieved through various mechanisms such as the modulation of the mitotic progression by agents like Nocodazole, Paclitaxel, and Colchicine, which affect microtubule dynamics. Similarly, the presence of Cyclin B1, a regulatory protein involved in mitosis, can potentially influence CDC14 activity.
Additionally, inhibitors of protein phosphatases like Okadaic Acid and Calyculin A, and inhibitors of protein kinases like Staurosporine, could potentially affect the pathways regulating CDC14. Likewise, the cyclin-dependent kinase inhibitor Roscovitine and the mTOR inhibitor Rapamycin, which both affect cell cycle progression, could potentially influence CDC14. Moreover, compounds that can arrest cells at specific cell cycle stages, like Hydroxyurea and Nitrogen Mustard, could potentially influence the activity of CDC14.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole is a microtubule-depolymerizing agent that can arrest cells at mitosis, potentially affecting CDC14 activity. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol is a microtubule-stabilizing agent that also influences mitotic progression, potentially affecting CDC14 activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic Acid is a potent inhibitor of protein phosphatases 1 and 2A, potentially affecting CDC14 indirectly. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is an inhibitor of protein phosphatases 1 and 2A, potentially affecting CDC14 indirectly. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Roscovitine is a cyclin-dependent kinase inhibitor that can affect cell cycle progression, potentially influencing CDC14. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Sodium Orthovanadate is a non-specific inhibitor of protein tyrosine phosphatases, potentially affecting CDC14 indirectly. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases, which could potentially affect CDC14's regulatory pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an inhibitor of mTOR, a protein involved in cell cycle progression, potentially affecting CDC14. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine is a microtubule-depolymerizing agent that can arrest cells at mitosis, potentially affecting CDC14 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Mechlorethamine HCl is an alkylating agent that can affect DNA replication and cell cycle progression, potentially influencing CDC14. | ||||||