Date published: 2026-4-27

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CCK Activators

CCK Activators constitute a class of chemical compounds that are associated with the modulation or enhancement of the biological activity of Cholecystokinin (CCK), a peptide hormone and neuropeptide found in the gastrointestinal tract and the central nervous system. CCK plays a vital role in various physiological processes, primarily in the digestive system, where it acts as a signaling molecule. This hormone is produced by specialized cells in the small intestine and released in response to the presence of food, particularly fatty and protein-rich meals. CCK is best known for its role in stimulating the contraction of the gallbladder, leading to the release of bile into the small intestine, which is essential for the digestion and absorption of dietary fats. CCK also influences appetite and satiety, as it acts on receptors in the brain to convey feelings of fullness and inhibit further food intake. CCK Activators are believed to interact with CCK or its receptors, altering the hormone's binding affinity or its signaling pathways. This modulation can impact the efficiency of gallbladder contractions and the regulation of digestive processes, affecting how the body responds to various nutrients. Furthermore, the influence of CCK on appetite regulation makes CCK Activators of interest in the study of feeding behavior and metabolic processes. Understanding how these activators affect CCK's functions provides insights into the intricate mechanisms governing digestion and satiety, which are critical aspects of overall health and nutritional balance in organisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

A-71623

130408-77-4sc-203487
1 mg
$284.00
1
(0)

A-71623 is distinguished by its role as a cholecystokinin (CCK) receptor agonist, engaging in specific molecular interactions that activate signaling pathways associated with digestive processes. Its unique structural conformation allows for high affinity binding to CCK receptors, influencing downstream effects on enzyme secretion and gastrointestinal motility. The compound's dynamic interaction with lipid membranes enhances its bioavailability, while its stability under physiological conditions supports sustained receptor activation.

Gastrin-1, rat

81123-06-0sc-397105
0.5 mg
$337.00
(0)

Gastrin-1, rat, functions as a potent stimulator of gastric acid secretion, engaging with specific receptors in the gastric mucosa. Its unique peptide structure facilitates interactions with the CCK-B receptor, triggering intracellular signaling cascades that enhance gastric motility and enzyme release. The compound exhibits rapid kinetics in receptor binding, leading to swift physiological responses. Additionally, its stability in the gastrointestinal environment ensures effective modulation of digestive processes.

Devazepide

103420-77-5sc-203562
sc-203562A
5 mg
50 mg
$245.00
$1030.00
1
(1)

A potent and selective antagonist of the CCK-A receptor, devazepide can indirectly increase CCK activity by blocking inhibitory feedback mechanisms.

Proglumide

6620-60-6sc-460085
sc-460085A
1 g
25 g
$320.00
$681.00
(0)

Proglumide, a non-selective CCK receptor antagonist, can indirectly promote CCK activity by reducing competitive inhibition at its receptors.

Famotidine

76824-35-6sc-205691
sc-205691A
500 mg
1 g
$65.00
$111.00
(0)

Famotidine, another H2 receptor antagonist, can indirectly promote CCK activity by reducing gastric acid secretion, thus influencing CCK release.

Cimetidine

51481-61-9sc-202996
sc-202996A
5 g
10 g
$62.00
$86.00
1
(1)

Cimetidine, a histamine H2 receptor antagonist, can enhance CCK secretion indirectly by modulating gastric acid levels, which are closely related to CCK activity.

Ranitidine

66357-35-5sc-203679
1 g
$193.00
(1)

As an H2 receptor antagonist, ranitidine can indirectly increase CCK activity through its effects on gastric acid secretion, which affects CCK release.

Nizatidine

76963-41-2sc-205771
sc-205771A
5 g
10 g
$72.00
$140.00
(1)

Nizatidine, another H2 receptor antagonist, may indirectly stimulate CCK activity by influencing gastric acid levels, thereby affecting CCK secretion.

Roxatidine

78273-80-0sc-280071A
sc-280071
1 mg
10 mg
$61.00
$459.00
1
(0)

Roxatidine, an H2 receptor antagonist, indirectly enhances CCK activity by modulating gastric acid secretion, a process that is linked to CCK release.

Omeprazole

73590-58-6sc-202265
50 mg
$67.00
4
(1)

Omeprazole, a proton pump inhibitor, can indirectly increase CCK activity by altering gastric acid secretion, which plays a role in CCK regulation.