A-71623 is a tetrapeptide that acts as a robust and selective CCK (cholecystokinin) receptor agonist. CCK is a neuroendocrine peptide described to play an important role in cell growth, cell proliferation, and other biological functions. Studies report that in comparison to other cholecystokinin agonists A-71623 does not have a tyrosine residue in which sulfation is necessary for strong cholecystokinin agonist activity in larger peptides. The compound has been used in animal studies to suppress appetite.
1. Lin, C.W., et al. 1991. Mol. Pharmacol. 39: 346-351. PMID: 1706470
2. Asin, K.E., et al. 1992. Pharmacol. Biochem. Behav. 42: 699-704. PMID: 1513850
3. Cannon, J.B., et al. 1996. J Drug Target. 4: 69-78. PMID: 8894966
4. Carrillo, J., et al. 2009. Anticancer Drugs. 20: 527-533. PMID: 19407653
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